The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Microglial activity during postnatal development is required for infantile amnesia in mice. [PDF]
Stewart E +5 more
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Structural mapping of NTCP distinguishes its dual functionality as a hepatitis B virus receptor and bile acid transporter. [PDF]
Matsuzawa K +11 more
europepmc +1 more source
Insights into the pro-angiogenic effect of hydroxysafflor yellow A (HSYA): targeting HIF-1α and MMP9 in HMEC-1. [PDF]
Fu J +6 more
europepmc +1 more source
Formation of ag nanoparticles in CO<sub>2</sub>-responsive microemulsion fabricated by a bio-based surfactant based on rosin. [PDF]
Yan X +9 more
europepmc +1 more source
GC-MS based bioactive profiling of Phyllanthus niruri and its antibacterial potential through experimental and computational studies. [PDF]
Labu ZK +6 more
europepmc +1 more source
2D Topological Electrocatalysts with Spin-Orbit Coupling: Interplay between the "Electrochemical" and "Topological" Surface States. [PDF]
Liu H +5 more
europepmc +1 more source
ANALYSIS OF ACTIVITY CHARACTERISTICS IN PEDESTRIAN STREET SPACE USING SPACE-TIME DIAGRAM MODEL
Chen BAI, Tomonori Sano
openalex +2 more sources

