Results 271 to 280 of about 1,625,987 (302)

Functional Characterization and Pathogenicity Classification of PRRT2 Splice Variants in PRRT2‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu, Yu‐Lan Chen, Wan‐Bing Sun, Hong‐Fu Li, Zhi‐Ying Wu, Dian‐Fu Chen   +5 more
wiley   +1 more source

Attention-deficit hyperactivity disorder in spontaneously hypertensive rat strain SHR/NCrl is associated with specific expression of uncoupling proteins, glucose transporter 1 and BACE1. [PDF]

Front Cell Neurosci
Sato T, Schreckenberg R, Schlüter KD.
europepmc   +1 more source

Plasma p‐tau181 as a Marker of Conversion to Alzheimer's Disease Dementia and Worsening in Cognitive Functions in Subjective Cognitive Decline and Mild Cognitive Impairment: A Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Plasma p‐tau181 has proven to be a promising diagnostic and prognostic tool in the earliest phases of Alzheimer's disease (AD). We aimed to evaluate the prognostic role of p‐tau181 in predicting conversion to AD dementia and worsening in cognition in mild cognitive impairment (MCI) and subjective cognitive decline (SCD).
Giulia Giacomucci, Assunta Ingannato, Chiara Crucitti, Silvia Bagnoli, Elisa Marcantelli, Sonia Padiglioni, Valentina Moschini, Carmen Morinelli, Laura Falsini, Sandro Sorbi, Valentina Berti, Benedetta Nacmias, Valentina Bessi   +12 more
wiley   +1 more source

Xuetongsu attenuates bone destruction in rheumatoid arthritis by suppressing RANKL/RANK/NFATc1 pathway to inhibit osteoclastogenesis and bone resorption. [PDF]

Bone Joint Res
Zheng H, Deng Y, Li B, Huang J, Liu J, Yang Y, Chen Y, Mao L, Li Y, Liu Y, Wang W, Yu H.   +11 more
europepmc   +1 more source

Enhanced multienzyme catalytic activity of Mn MOF induced by bioligands for efficient tumor therapy. [PDF]

J Nanobiotechnology
Ke J, Tian Y, Zhang T, Li A, Zhou Y, Cao Y, Wang L.   +6 more
europepmc   +1 more source

TET1 modulates trophoblast function by regulation of ODC1 in preeclampsia. [PDF]

Sci Rep
Fan C, Kang Y, Fang Z, Liu L, Wang C, Zhao M, Xiao L, Zhang C.   +7 more
europepmc   +1 more source

Cajal's legacy in the digital era: from neuroscience foundations to deep learning. [PDF]

Front Neuroanat
García-Lorenzo M, Herreras O, DeFelipe J.   +2 more
europepmc   +1 more source

Neutrophil extracellular traps: a novel contributor to vascular calcification in chronic kidney disease. [PDF]

Front Immunol
Wang Y, Li W, Liang Y, Wan J.
europepmc   +1 more source