Results 61 to 70 of about 1,625,987 (302)

The place of the Sun among the Sun-like stars [PDF]

, 2013
Context. Monitoring of the photometric and chromospheric HK emission data series of stars similar to the Sun in age and average activity level showed that there is an empirical correlation between the average stellar chromospheric activity level and the ...
Cessateur, G., Rozanov, E., Schmutz, W., Shapiro, A. I.   +3 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

PEMODELAN ELEARNING PERGURUAN TINGGI DENGAN MENGGUNAKAN FRAMEWORK LEARNING TECHNOLOGY SYSTEM ARCHITECTURE (LTSA) DAN UNIFIED MODELING LANGUAGE (UML)

JUTI: Jurnal Ilmiah Teknologi Informasi, 2017
Saat ini, perguruan tinggi sebagai motor pencerdas bangsa dituntut untuk lebih melek dengan perkembangan informasi teknologi, perkembangan peralatan komunikasi dan jaringan internet berkecepatan tinggi saat ini.
Harco Leslie Hendric Spits Warnars
doaj   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

FEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

UN PATRÓN DE INTERACCIÓN ENTRE DIAGRAMAS DE ACTIVIDADES UML Y SISTEMAS WORKFLOW AN INTERACTION PATTERN BETWEEN UML ACTIVITY DIAGRAMS AND WORKFLOW SYSTEMS

Revista EIA, 2008
Actualmente en los ambientes de desarrollo de software hay un gran interés en buscar y desarrollar técnicas que puedan integrar los sistemas transaccionales con los flujos de trabajo que soportan los procesos del negocio de las organizaciones.
Marta Silvia Tabares, Juan Diego Pineda, Andrés Felipe Barrera   +2 more
doaj  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Generic phase diagram of active polar films

, 2008
We study theoretically the phase diagram of compressible active polar gels such as the actin network of eukaryotic cells. Using generalized hydrodynamics equations, we perform a linear stability analysis of the uniform states in the case of an infinite ...
B. Alberts, J. F. Joanny, J. Howard, J. Kim, J. Prost, K. Takiguchi, P. G. De Gennes, R. Voituriez, T. Sekine, Y. Nonomura   +9 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Pseudoternary Phase Diagram and Antibacterial Activity of Microemulsion-Based Citronella Oil

Indonesian Journal of Chemistry
Citronella oil (CTO) is extracted from citronella leaves by maceration or steam distillation process, which has antibacterial and insect-repellent activities.
Chintya Gunarto, Alchris Woo Go, Artik Elisa Angkawijaya, Jenni Lie, Felycia Edi Soetaredjo, Suryadi Ismadji, Nathania Puspitasari, Jindrayani Nyoo Putro, Chandra Risdian   +8 more
doaj   +1 more source