Results 81 to 90 of about 659,826 (317)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
A framework for verifying deadlock and nondeterminism in UML activity\n diagrams based on CSP [PDF]
, 2019 Lucas Ramos Costa Lima +2 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Object Oriented Approach for developing of a Tutorial System Work Security and Health in SMEs [PDF]
Informatică economică, 2007 This paper presents the authors' research for developing a tutorial system which enables the delivery of proper training to specialized personnel in Small and Middle Enterprises (SMEs), in order to eliminate or reduce the health and safety risks of these
doaj
Mapping Activity Diagram to Fuzzy GSPN
International Journal of Computer Applications, 2013 Non-functional requirements’ assessment of enterprise architecture in system development, is important for organizations, and makes them protected from additional costs. For this goal Organizations should model their data and processes. Nowadays UML is considered as the most important modeling language, but because it’s a semi-formal language, it’s not
Ali Harounabadi, Elmira Kolyaie
openaire +1 more source
Influence of Metallic Ions on the Electrochemical Activity of Electrodes Based on Pourbaix Diagrams for Vanadium Redox Flow Battery [PDF]
, 2012 Chengming Zhao +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Kovalen: Jurnal Riset KimiaAnthocyanin compounds as natural coloring substances contained in Clitoria ternatea flowers have higher antioxidant activity than anthocyanins from other flower extracts.
Laily Isna Ramadhani +3 more
doaj +1 more source