Results 71 to 80 of about 902,851 (265)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
An acoustic activity recognition based on deep reinforcement learning
上海师范大学学报. 自然科学版, 2020 Most of previous research normally relied on specific data and manual filtering of outliers for better performance.In this paper,a new strategy of activity recognition was proposed which was entirely free from the constraint of user data and guaranteed ...
LIU Ming, HUANG Jifeng, GAO Hai
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Improving IoT Predictions through the Identification of Graphical Features
Sensors, 2019 IoT sensor networks have an inherent graph structure that can be used to extract graphical features for improving performance in a variety of prediction tasks.
Syeda Akter, Lawrence Holder
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Exploring Semi-Supervised Methods for Labeling Support in Multimodal Datasets
Sensors, 2018 Working with multimodal datasets is a challenging task as it requires annotations which often are time consuming and difficult to acquire. This includes in particular video recordings which often need to be watched as a whole before they can be labeled ...
Alexander Diete +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Fusing Object Information and Inertial Data for Activity Recognition
Sensors, 2019 In the field of pervasive computing, wearable devices have been widely used for recognizing human activities. One important area in this research is the recognition of activities of daily living where especially inertial sensors and interaction sensors ...
Alexander Diete, Heiner Stuckenschmidt
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Sensors, 2018 With the recent advancement in wearable computing, sensor technologies, and data processing approaches, it is possible to develop smart clothing that integrates sensors into garments.
Eliasz Kańtoch
doaj +1 more source