Results 221 to 230 of about 18,332,721 (387)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Exploration of the Fusidic Acid Structure Activity Space for Antibiotic Activity. [PDF]

Molecules
Kang YS, Silva SC, Smith K, Sumida K, Wang Y, Chiaraviglio L, Donthiri RR, Aljahdali AZ, Kirby JE, O'Doherty GA.   +9 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Life Space and Activity Space Measurement: Making "Room" for Structural Racism. [PDF]

Gerontologist
Szanton SL, Alexander KA, Kim B, Li Q, Gee GC, Bandeen-Roche KJ, Adkins-Jackson PB, Hladek MD, Samuel LJ, Haozous EA, Okoye SM, Crews DC, Thorpe RJ.   +12 more
europepmc   +1 more source

Beyond Activity Space: Detecting Communities in Ecological Networks. [PDF]

Ann Am Assoc Geogr, 2020
Xi W, Calder CA, Browning CR.
europepmc   +1 more source

Rapid bactericidal activity of an amphiphilic polyacrylate terpolymer system comprised of same-centered comonomers with 2-carbon and 6-carbon spacer arms and an uncharged repeat unit

, 2017
Kamia Punia, Ashish Punia, Kaushiki Chatterjee, Sumit Mukherjee, Jimmie E. Fata, Probal Banerjee, Krishnaswami Raja, Nan‐Loh Yang   +7 more
openalex   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The moderating effect of access to food facilities and recreational activity space on mHealth multiple health behavior change intervention. [PDF]

J Behav Med
Battalio SL, Barrett BW, Arnaoudova II, Press DJ, Hedeker D, Pfammatter AF, Kershaw KN, Spring B.   +7 more
europepmc   +1 more source

Is Smoking Cessation in Young Adults Associated With Tobacco Retailer Availability in Their Activity Space? [PDF]

Nicotine Tob Res, 2020
Shareck M, Datta GD, Vallée J, Kestens Y, Frohlich KL.   +4 more
europepmc   +1 more source

Activity Spaces in Multimodal Transportation Networks: A Nonlinear and Spatial Analysis Perspective [PDF]

Ke Guo, Rui Tang, Haixiao Pan, Dongming Zhang, Yang Liu, Zhuangbin Shi   +5 more
openalex   +1 more source