Results 41 to 50 of about 4,049,670 (304)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Assimilation of ICON/MIGHTI Wind Profiles into a Coupled Thermosphere/Ionosphere Model Using Ensemble Square Root Filter

Remote Sensing
Precise characterization of the thermospheric neutral wind is essential for comprehending the dynamic interactions within the ionosphere-thermosphere system, as evidenced by the development of models like HWM and the need for localized data.
Meng Zhang, Xiong Hu, Yanan Zhang, Zhaoai Yan, Hongyu Liang, Junfeng Yang, Cunying Xiao, Cui Tu   +7 more
doaj   +1 more source

Can a Spacecraft Use Solar Panels at Saturn? [PDF]

, 2001
This hands-on activity is designed to introduce students to the complexities of using solar panels in space exploration.

core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Investigating the Electric Field Influence on Total Ionization Dose Effects in Space Radiation for Carbon Nanotube Field Effect Transistors

IEEE Access
Carbon nanotube field effect transistors (CNTFETs) are considered ideal components for radiation-hardened integrated circuits (ICs) due to their material and structural properties.
Yanan Liang, Qian Chen, Rui Chen, Runjie Yuan, Ziyu Wang, Hailong Yu, Jianwei Han   +6 more
doaj   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Space Weather and Low‐Altitude Drone Economy

Space Weather
Unmanned Aerial Vehicles (UAVs) are becoming integral to the emerging low‐altitude economy, operating primarily below 3,000 m for applications such as logistics, inspection, precision agriculture, and urban air mobility.
Dabin Xue, Qing‐He Zhang, Xueshang Feng, Chi Wang   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Solar Radio Wide‐Band Spectroscopy and Imaging Facilities of the Chinese Meridian Project Phase II

Space Weather
Solar eruptions, including flares and coronal mass ejections, are the most energetic phenomena in the solar system. These explosive events accelerate high‐energy particles and generate electromagnetic radiation from radio to gamma‐ray wavelengths ...
Yihua Yan, Wei Wang, Linjie Chen, Jin Fan, Yao Chen, Shuwang Chang, Fabao Yan, Lihong Geng, Sha Li, Cang Su, Zhijun Chen, Chengming Tan, Bing Wang, Guang Lu, Chuanyang Li, Zhichao Zhou, Fei Liu, Suli Ma, Jun Cheng, Jing Du   +19 more
doaj   +1 more source