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The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Some of the next articles are maybe not open access.
CHI '97 extended abstracts on Human factors in computing systems looking to the future - CHI '97, 1997
This tutorial introduces participants to Activity Theory, a conceptual approach that provides a broad framework for describing the structure, development, and context of computer-supported activities. The tutorial will consist of lectures, discussion and small group exercises. A Web community will be established so attendees will be able to continue to
Victor Kaptelinin, Bonnie A. Nardi
openaire +1 more source
This tutorial introduces participants to Activity Theory, a conceptual approach that provides a broad framework for describing the structure, development, and context of computer-supported activities. The tutorial will consist of lectures, discussion and small group exercises. A Web community will be established so attendees will be able to continue to
Victor Kaptelinin, Bonnie A. Nardi
openaire +1 more source
2003
The rise of personal computer challenged mainframes systems for automation of existing work routine. Furthermore it brought forth a need to focus on how to work on materials and objects through the computer. In search for theoretical and methodical perspectives it seemed promising to turn towards the young HCI research tradition.
Bødker, Susanne, Bertelsen, Olav Wedege
openaire +4 more sources
The rise of personal computer challenged mainframes systems for automation of existing work routine. Furthermore it brought forth a need to focus on how to work on materials and objects through the computer. In search for theoretical and methodical perspectives it seemed promising to turn towards the young HCI research tradition.
Bødker, Susanne, Bertelsen, Olav Wedege
openaire +4 more sources
2015
The current chapter focuses on activity theory. The idea of activity theory is that the activity is a minimal meaningful context to understand human behavior. This theory, in short, highlights the relationship between an individual (subject) and an object of doing to achieve an outcome.
+4 more sources
The current chapter focuses on activity theory. The idea of activity theory is that the activity is a minimal meaningful context to understand human behavior. This theory, in short, highlights the relationship between an individual (subject) and an object of doing to achieve an outcome.
+4 more sources
2010
In this chapter I will give an account of some ideas in the Russian Theory of Activity or Activity Theory (AT) that have influenced the Activity Domain Theory (ADT): activity, mediation, and meaning. The activity domain in ADT is a direct descendant from “activity” in AT, while “mediation” and “meaning” are necessary prerequisites for the activity ...
openaire +2 more sources
In this chapter I will give an account of some ideas in the Russian Theory of Activity or Activity Theory (AT) that have influenced the Activity Domain Theory (ADT): activity, mediation, and meaning. The activity domain in ADT is a direct descendant from “activity” in AT, while “mediation” and “meaning” are necessary prerequisites for the activity ...
openaire +2 more sources
Reflections on activity theory
Educational Review, 2009It is sometimes suggested that activity theory represents the most important legacy of Soviet philosophy and psychology. But what exactly is activity theory? The canonical account in the West is given by Engestrom, who identifies three stages in the theory’s development: from Vygotsky’s insights, through Leontiev’s articulation of the fundamental ...
openaire +1 more source