Results 241 to 250 of about 3,944,530 (288)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source
Some of the next articles are maybe not open access.

Activity theory

CHI '97 extended abstracts on Human factors in computing systems looking to the future - CHI '97, 1997
This tutorial introduces participants to Activity Theory, a conceptual approach that provides a broad framework for describing the structure, development, and context of computer-supported activities. The tutorial will consist of lectures, discussion and small group exercises. A Web community will be established so attendees will be able to continue to
Victor Kaptelinin, Bonnie A. Nardi
openaire   +1 more source

Activity Theory

2003
The rise of personal computer challenged mainframes systems for automation of existing work routine. Furthermore it brought forth a need to focus on how to work on materials and objects through the computer. In search for theoretical and methodical perspectives it seemed promising to turn towards the young HCI research tradition.
Bødker, Susanne, Bertelsen, Olav Wedege
openaire   +4 more sources

Activity Theory

2015
The current chapter focuses on activity theory. The idea of activity theory is that the activity is a minimal meaningful context to understand human behavior. This theory, in short, highlights the relationship between an individual (subject) and an object of doing to achieve an outcome.
  +4 more sources

Activity Theory

2010
In this chapter I will give an account of some ideas in the Russian Theory of Activity or Activity Theory (AT) that have influenced the Activity Domain Theory (ADT): activity, mediation, and meaning. The activity domain in ADT is a direct descendant from “activity” in AT, while “mediation” and “meaning” are necessary prerequisites for the activity ...
openaire   +2 more sources

Reflections on activity theory

Educational Review, 2009
It is sometimes suggested that activity theory represents the most important legacy of Soviet philosophy and psychology. But what exactly is activity theory? The canonical account in the West is given by Engestrom, who identifies three stages in the theory’s development: from Vygotsky’s insights, through Leontiev’s articulation of the fundamental ...
openaire   +1 more source

Activity Theory

Journal of the Learning Sciences, 1998
openaire   +2 more sources

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