Results 91 to 100 of about 359,175 (254)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Suspended Sentences and Free-Standing Probation Orders in U.S. Guidelines Systems: A Survey and Assessment [PDF]
, 2010 Much academic attention has been directed towards management models, but there is limited research into the details of how these models are put to use in organizations.
Elg, Mattias, Langstrand, Jostein
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
International Journal of Narrative Therapy and Community WorkTom Strong reviews Aysel Sultan (2022). Recovering assemblages: Unfolding sociomaterial relations of drug use and recovery. Palgrave Macmillan. 290pp. ISBN 978-981-19-1234-4, ISBN 978-981-19-1235-1 (eBook).
Tom Strong
doaj +1 more source
The gender of science: reflections on the actor-network theory and the feminist perspective
Mediações: Revista de Ciências Sociais, 2015 This article discusses some of the principles that guide the descriptive forms of the actor-network theory (ANT) of Bruno Latour and feminist standpoint theory formulated by Sandra Harding and Evelyn Fox Keller, through my research on the "Marie Curie ...
Gabriel Pugliese Cardoso
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Resources of actor-network theory for daily mobility researches [PDF]
, 2015 Resources of actor-network theory for daily mobility researches are examined. Reconstruction of social space term from ANT point of view allows understanding daily mobility as a phenomenon providing reproduction of social links.В работе рассматриваются ...
Danilova, A., Данилова, А. В.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Actor-Network Theory: Insights into the Study of Social-Ecological Resilience. [PDF]
Int J Environ Res Public Health, 2022 Yao S, Liu K.
europepmc +1 more source
Using Actor-Network Theory to understand planning practice: exploring relationships between actants in regulating low carbon commercial development [PDF]
, 2013 There has been a recent growth in interest within planning theory in Actor–Network Theory. This article explores the potential for Actor–Network Theory to deliver a distinctive perspective on planning practice.
Rydin, YJ
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Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source