Results 61 to 70 of about 359,175 (254)

An Actor-Network Theory conceptualization for smart specialization strategies (S3): creative brokerage towards sustainability transition

Entrepreneurship and Sustainability Issues
Smart Specialisation Strategies, their planning and implementation are becoming more important in Europe's transition but also bring up several challenges, especially when it comes to complex innovation processes and requirements arising from the call ...
Christopher Meyer
doaj   +1 more source

Epidemic space [PDF]

, 2005
The aim of this article is to highlight the importance of 'spatiality' in understanding the materialization of risk society and cultivation of risk sensibilities.
Anderson M, Beck U, Beck U, Bouter, Brewster DD, Cann AJ, Cannon G, Christie AB, Derrida J, Douglas M, Evans AS, Evans AS, Ewald P, Ewald P, Eyles J, Foucault M, Garret L, Gisselchrist D, Gisselchrist D, Grist NR, Haraway D, Heidegger M, Holland J, Johnson K, Joost van Loon, Latour B, Latour B, Latour B, Latour B, Lefebvre H, Levine A, Lilienfeld DA, Lupton D, Margulis L, McCormick JB, McNeill WH, Old RW, Peters CJ, Preston R, Rothschild H, Ryan F, Ryan F, Sapp J, Shields R, Shope RE, Sontag S, Treichler P, van Loon J, van Loon J, van Loon J, Wills C   +50 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Diásporas y transiciones en la Teoría del Actor-Red Diasporas and transitions in Actor-Network Theory

Athenea Digital, 2011
Este texto es una presentación del monográfico Diásporas y transiciones en la teoría del actor-red. Sus páginas presentan las principales características de esta teoría, una ...
Blanca Callén, Miquel Domènech, Daniel López, Israel Rodríguez Giralt, Tomás Sánchez-Criado, Francisco Javier Tirado Serrano   +5 more
doaj  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Michael Porter's Cluster Theory as a local and regional development tool – the rise and fall of cluster policy in the UK [PDF]

, 2013
There has been much written on industrial agglomeration, but it is Michael Porter’s cluster theory, above all others, which has come to dominate local and regional economic development policy. His work has been adopted by the OECD, EU, national and local
Swords, Jon
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

The Campaign: a case study in identity construction through performance [PDF]

, 2009
This article undertakes a detailed case study of The Campaign, a teaching and learning innovation in media and communications that uses an online educational role-play.
Riddle, Matthew
core   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source