Results 61 to 70 of about 1,138 (285)

Actor Network Model of the Construction Mechanism of a Technology Standardization Innovation Ecosystem—Haier Case Study

open access: yesSystems
As the competition of standards among enterprises turns to the competition among innovation ecosystems, how to construct the technology standardization innovation ecosystem (TSIE) is of great significance to enhance the competitiveness of enterprises and
Yu Yuan, Dengyun Ma
doaj   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

open access: yesAdvanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu   +11 more
wiley   +1 more source

Evolution of Physical Intelligence Across Scales

open access: yesAdvanced Intelligent Discovery, EarlyView.
By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu   +7 more
wiley   +1 more source

Testing the Social Investment Principle Around Childbirth: Little Evidence for Personality Maturation Before and After Becoming a Parent

open access: yesEuropean Journal of Personality, EarlyView., 2020
Abstract In line with the social investment principle, becoming a parent should lead to more mature behaviour and an increase in conscientiousness, agreeableness, and emotional stability. However, previous research provided mixed results that do not support this idea.
Eva Asselmann   +2 more
wiley   +1 more source

A Unifying Approach to Self‐Organizing Systems Interacting via Conservation Laws

open access: yesAdvanced Intelligent Discovery, EarlyView.
The article develops a unified way to model and analyze self‐organizing systems whose interactions are constrained by conservation laws. It represents physical/biological/engineered networks as graphs and builds projection operators (from incidence/cycle structure) that enforce those constraints and decompose network variables into constrained versus ...
F. Barrows   +7 more
wiley   +1 more source

Challenging the User-Avatar Dichotomy in Avatar Customization Research

open access: yesEludamos, 2018
The work presented here represents an Actor-Network Theory (ANT) approach to the study of self-representation in games. Though the development of a novel analytical framework we aim to challenge the anthropocentric approach that is all too common to ...
Victoria McArthur
doaj   +1 more source

Towards Advanced Intelligent and Perceptive Soft Grippers

open access: yesAdvanced Intelligent Systems, EarlyView.
Implementing soft yet strong and intelligent soft grippers request innovative and creative solutions in designing soft bodies and seamlessly integrating actuated systems with hierarchical sensing. This review systematically analyses soft grippers with a deep understanding of core components, from fundamental design principles to actuation and sensing ...
Haneul Kim   +4 more
wiley   +1 more source

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