Results 41 to 50 of about 174,978 (297)

PENGARUH STRES INTERNAL DAN STRES EKSTERNAL PADA COPING DIADIK NEGATIF

open access: yesJurnal Psikologi Ulayat: Indonesian Journal of Indigenous Psychology, 2012
A lot of research found the negative effect of stress on the ability of couples to cope. This present study tried to further study this phenomenon by differentiating the source of stress and using dyadic analysis. This study tested the effect of external
Yonathan Aditya Goei
doaj   +1 more source

ContextErlang: introducing context-oriented programming in the actor model

open access: yes, 2012
Self-adapting systems are becoming widespread in emerging fields such as autonomic, mobile and ubiquitous computing. Context-oriented programming (COP) is a promising language-level solution for the implementation of contextaware, self-adaptive software.
Guido Salvaneschi   +4 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A generic synchronous dataflow architecture to rapidly prototype and deploy robot controllers

open access: yesInternational Journal of Advanced Robotic Systems, 2020
The article presents a software architecture to optimize the process of prototyping and deploying robot controllers that are synthesized using model-based design methodologies. The architecture is composed of a framework and a pipeline.
Diego Ferigo   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Understanding dynamics of information transmission in Drosophila melanogaster using a statistical modeling framework for longitudinal network data (the RSiena package)

open access: yesFrontiers in Psychology, 2016
Social learning – the transmission of behaviors through observation or interaction with conspecifics – can be viewed as a decision-making process driven by interactions among individuals.
Cristian ePasquaretta   +9 more
doaj   +1 more source

Notes Toward an Extimate Materialism: A Reply to Graham Harman

open access: yesOpen Philosophy, 2021
This article mounts a defense of my and Slavoj Žižek’s co-edited anthology, Subject Lessons: Hegel, Lacan, and the Future of Materialism, against the two main criticisms of it made throughout Graham Harman’s article “The Battle of Objects and Subjects”: (
Sbriglia Russell
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Actor-only in comparison with actor-critic learning.

open access: yes, 2019
The columns labeled with ‘action value 1’ (panels a and d) and ‘action value 2’ (panels b and d) show the simulated evolution of the collective synaptic weights G and N of the actor network over 30 successive trials.
Rafal Bogacz (307953)   +1 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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