Results 41 to 50 of about 305 (210)
Overcoming hierarchy in business model innovation: an actor-oriented approach [PDF]
European Journal of Innovation Management, 2020 PurposeBusiness model innovation is a key element for firms' competitiveness. Its development can be supported by the establishment of an actor-oriented scheme to overcome hierarchical structures. The actor-oriented scheme is characterized by intra-organizational networks of relationships that can be established and dissolved between individuals ...
Di Toma, Paolo, Ghinoi, Stefano
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Benchmarking Fault-Tolerance Characteristics of Actor-Based Runtimes
ComputersFault tolerance is a fundamental requirement of distributed systems, and actor-based runtimes provide a widely adopted approach for building resilient and highly concurrent applications. Although several actor ecosystems offer mechanisms for supervision,
Luís Nogueira, Jorge Coelho
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Frontiers in Psychology, 2016 Social learning – the transmission of behaviors through observation or interaction with conspecifics – can be viewed as a decision-making process driven by interactions among individuals.
Cristian ePasquaretta +9 more
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Notes Toward an Extimate Materialism: A Reply to Graham Harman
Open Philosophy, 2021 This article mounts a defense of my and Slavoj Žižek’s co-edited anthology, Subject Lessons: Hegel, Lacan, and the Future of Materialism, against the two main criticisms of it made throughout Graham Harman’s article “The Battle of Objects and Subjects”: (
Sbriglia Russell
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Humanities & Social Sciences CommunicationsSince 2009, the Chinese government has introduced a series of policies aimed at expanding youth football participation and addressing the shortage of talent reserves.
Yingwen Chen +3 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Typology of Business Models in the Smart Economy: An Ontological Approach to Transforming the Logic of Value Creation [PDF]
Problemi EkonomikiThe aim of the article is to develop an integrated typology of enterprise business models in the smart economy based on the ontological approach and to form a coherent conceptual framework that combines structural, activity-based, innovative, and ...
Verba Veronika A. , Osokin Hennadii V.
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