Results 51 to 60 of about 50,813 (305)

A midrange theory of local cross-sector action based on the actor-network theory

open access: yesSSM: Qualitative Research in Health, 2022
Given the value of cross-sector collaborations in solving complex societal problems, experts are now recommending that research focus on documenting process–effect linkages.
Angèle Bilodeau   +5 more
doaj   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

open access: yesAdvanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia   +6 more
wiley   +1 more source

Challenging the User-Avatar Dichotomy in Avatar Customization Research

open access: yesEludamos, 2018
The work presented here represents an Actor-Network Theory (ANT) approach to the study of self-representation in games. Though the development of a novel analytical framework we aim to challenge the anthropocentric approach that is all too common to ...
Victoria McArthur
doaj   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li   +12 more
wiley   +1 more source

An efficient deep learning model for brain tumour detection with privacy preservation

open access: yesCAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Internet of medical things (IoMT) is becoming more prevalent in healthcare applications as a result of current AI advancements, helping to improve our quality of life and ensure a sustainable health system. IoMT systems with cutting‐edge scientific capabilities are capable of detecting, transmitting, learning and reasoning.
Mujeeb Ur Rehman   +8 more
wiley   +1 more source

Corruption in migration management: a network perspective [PDF]

open access: yes, 2018
This paper explores the relation between networks as an emerging mode of public governance and corruption. Adopting the theoretical lens of actor-network theory (ANT), the paper investigates an Italian episode of corruption related to the awarding of ...
Callon M   +15 more
core   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

open access: yesAdvanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Effective coordination of vertical IS standardisation initiatives [PDF]

open access: yes, 2010
This paper investigates vertical IS standardisation initiatives from an Actor Network Theory (ANT) perspective. It describes the standardisation process as a series of translations of interests.
Carr, Rodney, Saundage, Dilal
core   +1 more source

Visualization in analysis: developing ANT Analysis Diagrams (AADs) [PDF]

open access: yes, 2016
This article presents a novel diagramming approach which employs aspects of Actor-Network Theory (ANT) in the creation of ANT Analysis Diagrams (AADs).
Payne, Lisa
core   +1 more source

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