Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Localisation beyond the international-local divide: paternalism and politicisation in humanitarian response in Dominica and Turkey. [PDF]
Disastersde Koeijer V, Sahin B.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Co-creation in research, policy engagement and advocacy: Lessons and limits from two decades of practice at the African Population and Health Research Center. [PDF]
PLOS Glob Public HealthOtukpa EO, Ziraba AK, Bain LE.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Collage of 19th century popular actors
Collection of studio portraits of entertainers, actors and actresses who performed on the American stage in the mid-1800s. Caption on image: Popular Actors No.
Ashford, Brothers & Co.
core
Theatre-Neuroscience: a brief perspective on the use of neuroscientific techniques to measure interpersonal coordination and the sense of self in theatrical contexts. [PDF]
Oxf Open NeurosciGreaves DA.
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Advancing relational methods in agri-food governance research and beyond: Introducing the Socio-Material Actor-Network Analysis (SMANA) methodology. [PDF]
Open Res EurZerbian T, Furlan V, López-García D.
europepmc +1 more source