Results 231 to 240 of about 2,042,802 (273)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Strengthening and sustaining gender-based violence (GBV) coordination in emergencies: a synthesis of practitioner-driven, globally applicable recommendations. [PDF]

Confl Health
Raftery P, Potts A, Hyde M, Wuyke YY, Hashmey H, Munezero L, Kiss L, Hossain M, Palmer J.   +8 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

From Lineage Property to Individual Property: Dynamics of Land Management in the Villages of Nasso and Dindéresso, Hauts-Bassins, Burkina Faso. [PDF]

Open Res Afr
Sawadogo A.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The family, school and community linkage of improving adolescent physical fitness and health: based on the ANT. [PDF]

Front Psychol
Liu Y, Zhu Q, Li S, Yao L, Wang D.
europepmc   +1 more source

Rethinking local welfare: a network analysis of an Italian case study. [PDF]

Front Sociol
Carbone S.
europepmc   +1 more source

The Ocean Equity Index. [PDF]

Nature
Blythe JL, Claudet J, Gill D, Ban NC, Epstein G, Gurney GG, Jupiter SD, Mahajan SL, Mangubhai S, Turner R, Bennett NJ, D'Agata S, Franks P, Lau J, Ahmadia G, Andrachuk M, Annasawmy P, Brun V, Darling ES, Di Franco A, Evans L, Lazzari N, Naggea J, Relano V, Pertuz MC, Villasante S, Zafra-Calvo N.   +26 more
europepmc   +1 more source