Results 161 to 170 of about 250,870 (282)

Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions

open access: yesBiotechnology Progress, EarlyView.
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal   +5 more
wiley   +1 more source

Integrated Selective Depolymerization and Downstream Processing for Mixed Polyester Waste, Part 1

open access: yesChemie Ingenieur Technik, EarlyView.
Chemical recycling of mixed plastics by hydrolysis generates dilute monomer mixtures requiring complex downstream purification. To overcome this challenge, upstream selectivity is targeted. Tailored reaction conditions enable cascaded depolymerization which is shown for a PLA/PET model system.
Fabian Roweda, Filip Latz, Andreas Jupke
wiley   +1 more source

Restricted Tweedie stochastic block models

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract The stochastic block model (SBM) is a widely used framework for community detection in networks, where the network structure is typically represented by an adjacency matrix. However, conventional SBMs are not directly applicable to an adjacency matrix that consists of nonnegative zero‐inflated continuous edge weights.
Jie Jian, Mu Zhu, Peijun Sang
wiley   +1 more source

An observation‐driven state‐space model for claims size modelling

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract State‐space models are popular in econometrics. Recently, these models have gained some popularity in the actuarial literature. The best known state‐space models are of the Kalman‐filter type. These are called parameter‐driven because the observations do not impact the state‐space dynamics.
Jae Youn Ahn   +2 more
wiley   +1 more source

Playing with fire? A mean‐field game analysis of fire sales and systemic risk under regulatory capital constraints

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract We analyze the effect of regulatory capital constraints on financial stability in a large homogeneous banking system using a mean‐field game (MFG) model. Each bank holds cash and a tradable risky asset. Banks choose absolutely continuous trading rates in order to maximize expected terminal equity, with trades subject to transaction costs ...
Rüdiger Frey, Theresa Traxler
wiley   +1 more source

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