Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal +5 more
wiley +1 more source
Research note: Application and validation of RP-HPLC for quantifying ovomucoid, lysozyme, ovotransferrin, and ovalbumin in commercial pasteurized egg white. [PDF]
Sousa I +6 more
europepmc +1 more source
Integrated Selective Depolymerization and Downstream Processing for Mixed Polyester Waste, Part 1
Chemical recycling of mixed plastics by hydrolysis generates dilute monomer mixtures requiring complex downstream purification. To overcome this challenge, upstream selectivity is targeted. Tailored reaction conditions enable cascaded depolymerization which is shown for a PLA/PET model system.
Fabian Roweda, Filip Latz, Andreas Jupke
wiley +1 more source
A Transient Two-Phase Productivity Forecasting Method in Fractured Nanoporous Shale Gas Reservoirs. [PDF]
Zhang R, He S, Zhang Q, Xiao H, Zhang L.
europepmc +1 more source
Restricted Tweedie stochastic block models
Abstract The stochastic block model (SBM) is a widely used framework for community detection in networks, where the network structure is typically represented by an adjacency matrix. However, conventional SBMs are not directly applicable to an adjacency matrix that consists of nonnegative zero‐inflated continuous edge weights.
Jie Jian, Mu Zhu, Peijun Sang
wiley +1 more source
Modeling and Validation of Electrostatic Sensing for UAV Targets in High-Dynamic Encounter Scenarios. [PDF]
Xia R +5 more
europepmc +1 more source
An observation‐driven state‐space model for claims size modelling
Abstract State‐space models are popular in econometrics. Recently, these models have gained some popularity in the actuarial literature. The best known state‐space models are of the Kalman‐filter type. These are called parameter‐driven because the observations do not impact the state‐space dynamics.
Jae Youn Ahn +2 more
wiley +1 more source
A Theoretical Solution for Analyzing Bi-Layer Structures with Differing Thermal Properties. [PDF]
Peng Q, Zhou S, Shi Y, Qian X.
europepmc +1 more source
Abstract We analyze the effect of regulatory capital constraints on financial stability in a large homogeneous banking system using a mean‐field game (MFG) model. Each bank holds cash and a tradable risky asset. Banks choose absolutely continuous trading rates in order to maximize expected terminal equity, with trades subject to transaction costs ...
Rüdiger Frey, Theresa Traxler
wiley +1 more source
Plasma pharmacokinetics, milk residue depletion profile, and milk withdrawal interval estimation following multiple-dose oral administration of meloxicam to lactating dairy goats. [PDF]
Mercer MA +7 more
europepmc +1 more source

