Results 111 to 120 of about 5,402,583 (289)
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Impact of triaxial stress state at various pavement depths on the dynamic modulus of asphalt mixture
The mechanical characteristics of asphalt mixture are closely related with its stress state, temperature, and loading rate, therefore, the loading condition of the asphalt mixture's dynamic modulus test should be consistent with the actual temperature ...
Jun Zhang, Ye Wang, Xudong Wang, Hao Chu
doaj +1 more source
Fifty years ago, one of the worldwide first industrial production processes to produce fission-Mo-99 for medical use had been started at ZfK Rossendorf (now: HZDR, Germany).
S. Dittrich
doaj +1 more source
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah +6 more
wiley +1 more source
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
"Employment Effects of the 2009 Minimum Wage Increase: Evidence from State Comparisons of At-Risk Workers" [PDF]
In July, 2009, the U.S. Federal minimum wage was increased from $6.55 to $7.25. Individuals in some states were unaffected by this increase, since the state minimum wage already exceeded $7.25 and the state minimum was not increased further.
Chenglong Ke, Saul D. Hoffman
core
This study explores the lightweight potential of laser additive‐manufactured NiTi triply periodic minimal surface sheet lattices. It systematically investigates the effects of relative density and unit cell size on surface quality, deformation recovery, compression behavior, and energy absorption.
Haoming Mo +3 more
wiley +1 more source
Actual problems of state service reform
The article analyzes the draft federal law "On the Judicial Service of the Russian Federation", proposed by the Presidium of the Council of Judges. The draft law is justified in the idea of creating a system of public service of the Russian Federation, an independent type of service - the judiciary.
openaire +1 more source
The actual surface state of optics surfaces [PDF]
The surfaces of precision optics components made of glass such as lenses or prisms are commonly supposed to be of high purity and cleanliness. However, several effects and mechanisms may lead to contamination and modification of glass surfaces produced by conventional manufacturing, i.e., cutting, grinding, lapping, and polishing. Apart from mechanical
Gerhard, Christoph +2 more
openaire +1 more source

