LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
New agroclimatic approach for soybean sowing dates recommendation: A case study
Revista Brasileira de Engenharia Agrícola e Ambiental, 2014 The objective of this study was to introduce a new approach to recommend sowing dates for soybean crop in Brazil, considering the climatic conditions and crop yield.
Rafael Battisti, Paulo C. Sentelhas
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Evaluation of an application for dynamic feeding of dairy cows [PDF]
, 2009 Dynamic feeding is an innovative application for concentrate feeding of dairy cows. Daily individual settings are derived from the actual individual milk yield response to concentrate intake.
Andre, G. +2 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Is Federal Crop Insurance Policy Leading to Another Dust Bowl? [PDF]
, 2017 As the southern Great Plains get hotter and drier, is federal policy that encourages farmers not to adapt to climate change leading to another Dust Bowl?That's the troubling question raised by a new EWG report that shows how a provision in the federal ...
Anne Weir Schechinger, Craig Cox
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Actual and Potential Yield Levels of Potato in Different Production Systems of Japan [PDF]
Potato Research, 2016 This study was made possible by a grant of Hoikkaido University allowing Dr. Haverkort to spend two months in 2015 at the Department of Agriculture.
Deguchi, T. +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Studying the Beneficial Indicators of Intercropping of Safflower (Carthamus tinctorius L.) with Chickpea (Cicer arietinum L.), Lentil (Lens culinaris Medik), and Bitter Vetch (Lathyrus sativus L.) [PDF]
بوم شناسی کشاورزیIntroduction[1] Intercropping is an agroecological technique in which two or more species are grown in the same area for a certain period of time. These species should be complementary to each other regarding the use of productive resources. By selecting
Amin Yari +3 more
doaj +1 more source