Results 51 to 60 of about 37,622 (292)

Virtualiteit in Dietrich Bonhoeffer se Sanctorum Communio: Kollektiewe intelligensie as nuwe epistemologie vir die kerk?

open access: yesHTS Teologiese Studies/Theological Studies, 2016
Virtuality in Dietrich Bonhoeffers’ Sanctorum Communio: Collective intelligence as a new epistemology of the church? Collective intelligence has been indicated from biological, philosophical, anthropological and technological developments.
Deon du Toit
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Counterpart Theory and Actuality [PDF]

open access: yes
Lewis (The Journal of Philosophy, 65(5), 113–126, 1968) attempts to provide an account of modal talk in terms of the resources of counterpart theory, a first-order theory that eschews transworld identity.
Milford, James
core   +1 more source

Modality and Actuality: Lukács’s Criticism of Hegel in History and Class Consciousness

open access: yesOpen Philosophy
The present article tries to show the originality of Lukács’s theory of Actuality (Wirklichkeit) by comparing it with the same notion in Hegel’s Logic. It results that Lukács’s interpretation of Marxism and the Russian Revolution depends on a clear and ...
Rametta Gaetano
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Conditionals and Actuality

open access: yesErkenntnis, 2009
It is known that indicative and subjunctive conditionals interact differently with a rigidifying “actually” operator. The paper studies this difference in an abstract setting. It does not assume the framework of possible world semantics, characterizing “actually” instead by the type of logically valid formulas to which it gives rise.
openaire   +3 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

On the non-actuality inferences in Turkish avertives

open access: yesDilbilim Araştırmaları Dergisi
Languages have various forms of expressing implications ofimminency and non-actuality. While a variety of constructions such asimperfectives, proximatives or adverbs like almost crosslinguistically imply thecounterfactuality of the event in question ...
Furkan DİKMEN, Ömer DEMİROK
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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