Results 111 to 120 of about 28,487 (304)

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Kierkegaard's Concept of Actuality

open access: yes
The paper follows the development of the notion of “actuality” in Kierkegaard’s writings focusing on its relevance for an ethics-centered approach to human existence.
González, Darío David
core  

Psychic phenomena: meditation, perception actuality: an Australian study

open access: yes, 2007
This thesis presents the findings of an investigation into contemporary psychic phenomena as reported by Australian students. It asks the question: 'do people experience psychic phenomena?' The study is an empirical one of reported psychic phenomena ...
Nattress, Emma
core   +1 more source

Foucault and the question of actuality

open access: yes, 2023
Glavni raziskovalni problem magistrskega dela je usmerjen v problematiko »aktualnosti« in s tem povezano vpetost v čas, v katerem živimo. Izhajali smo iz Michela Foucaulta in njegovega odgovora na vprašanje »Kaj je razsvetljenstvo?«, ki je povezano s ...
Hötzl, Mihael
core  

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

Future Actuality and Truth Ascriptions

open access: yesPhilosophies
One question that arises in connection with Ockhamism, and that perhaps has not yet received the attention it deserves, is how a coherent formal account of truth ascriptions can be provided by using a suitable truth predicate in the object language.
Andrea Iacona, Giuseppe Spolaore
doaj   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato   +27 more
wiley   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

The Possibility of Knowledge in the Noble Quran [PDF]

open access: yesحکمت اسرا, 2010
Resorting to the noble Quran in resolving and answering the challenges presented by the humanities, in particular philosophy and epistemology, opens up new vistas in these sciences.
Seyyed Mohsen Miri
doaj  

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