Results 41 to 50 of about 28,487 (304)
HTS Teologiese Studies/Theological Studies, 2016 Virtuality in Dietrich Bonhoeffers’ Sanctorum Communio: Collective intelligence as a new epistemology of the church? Collective intelligence has been indicated from biological, philosophical, anthropological and technological developments.
Deon du Toit
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From Actuality to Concept in Hegel’s Logic
, 2017 This chapter examines Hegel’s treatment of the concept of actuality in his Science of Logic. It argues that Hegel’s treatment of actuality serves two functions: first, it provides the argument for the ‘genesis of the Concept’, Hegel’s version of Kant’s ...
Karen Ng
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
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Objective Reality as Nomic Actuality [PDF]
I argue for a new account of Kant's concept of objective reality. Objective reality should be understood as nomic actuality. The notion of nomic actuality is inspired by Kant's concept of nature in the most general sense, which describes the existence of
Hutterer, Alexander Maximilian
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Explaining A Narrative in The Critical Philosophy of History
Jurnal Filsafat, 2019 This paper explains the narrative in the study of history which has only been understood as a way of telling what should have happened, not what really happened.
Arif Akhyat
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Acta Universitatis Carolinae Theologica, 2022 Bonaventure’s epistemology is partly based on his Trinitarian theology. This paper investigates the Trinitarian connotations in this epistemology and their broader significance.
Jonathan Bieler
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Aristotle and Heidegger: Potentiality in Excess of Actuality
, 2016 Aristotle claims in book 9 of the Metaphysics that potentiality is distinct from actuality yet also that potentiality exists only for the sake of actuality. This essay presents the relationship between potentiality’s existence and actuality’s priority as
Brown, Nahum Carl HUMA
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
, 2013 In this paper, I defend an indexical analysis of the abstract-concrete distinction within the framework of modal realism. This analysis holds the abstract-concrete distinction to be conceptually inseparable from the distinction between the actual and the
Cowling, Sam
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
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