Results 171 to 180 of about 3,877,321 (353)
Type 2 diabetes (T2D) is known as one of the important risk factors for the severity and mortality of COVID-19. Here, we evaluate the impact of T2D and its genetic susceptibility on the severity and mortality of COVID-19, using 459,119 individuals in UK ...
Aeyeon Lee +8 more
doaj +1 more source
DNA methyltransferase inhibitors in hematological malignancies and solid tumors
Abstract Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5‐position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor ...
Valentin Wenger +3 more
wiley +1 more source
ABSTRACT Survival outcomes for adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) have improved with modern frontline therapies and minimal residual disease (MRD)‐guided strategies. As a result, allogeneic hematopoietic cell transplantation (HCT) is increasingly deferred in first remission (CR1) and used in the relapsed setting.
Oren Pasvolsky +24 more
wiley +1 more source
The Rise of Health Economics: Transforming the Landscape of Economic Research
ABSTRACT This paper explores the evolving role of health economics within economic research and publishing over the past 30 years. Historically, largely a niche field, health economics has become increasingly prominent, with the share of health economics papers in top journals growing significantly.
Lorenz Gschwent +3 more
wiley +1 more source
Abstract We compare the impact of two extension modalities on knowledge accumulation and willingness to pay for a weather index insurance product among smallholder farmers in Kenya. One approach to extension is based on experiential learning and involves participation in an incentivized framed experiment (or game).
Jamleck Osiemo +3 more
wiley +1 more source
Abstract In December 2023, the European Parliament and the Council reached an agreement to revise the Solvency II Directive, aiming to unlock €100 billion in private investment through a series of deregulatory measures. This marks a significant departure from the stringent insurance supervision framework that has shaped European policy since the ...
Cyril Benoît
wiley +1 more source
Abstract INTRODUCTION Blood‐based phosphorylated tau 217 (p‐tau217), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) show promise for Alzheimer's disease (AD), while their links to brain amyloid beta (Aβ)/tau, hippocampal atrophy, and cognitive decline need further investigation.
Feng‐Feng Pan +7 more
wiley +1 more source
How can actuarial science contribute to the field of health technology assessment? An interdisciplinary perspective. [PDF]
Espinosa O +4 more
europepmc +1 more source
Genetic testing and actuarial science – ERRATUM
A. Macdonald
semanticscholar +1 more source
ABSTRACT We conduct a timely comprehensive review of the existing literature on Task Force on Climate‐Related Financial Disclosures (TCFD). Our aim is to provide a synthesis and extension of the current literature as follows: (i) review theoretical (i.e., socio‐political, economic‐based and market‐based) perspectives employed by existing studies, (ii ...
Yunice Karina Tumewang +2 more
wiley +1 more source

