Results 111 to 120 of about 61,012 (228)

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

open access: yesNeurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao   +6 more
wiley   +1 more source

Salvia miltiorrhiza‐Derived Vesicle‐Like Nanoparticles Functionalised Hydrogel With Excellent Ability of Oxidative Stress Modulation and Anti‐Cardiomyocyte Apoptosis for Sepsis‐Induced Myocardial Injury

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT In the process of myocardial cell structural and functional damage caused by various factors, current therapeutic strategies primarily focus on restoring myocardial blood supply, often neglecting the inherent complex microenvironment triggered by elevated reactive oxygen species (ROS) levels during myocardial injury.
Zhichao Liu   +12 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

open access: yesPhotochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew   +3 more
wiley   +1 more source

Cervical epidural catheter for administration of detomidine and morphine in a model of carpal synovitis in the horse

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To determine the analgesic effects of detomidine and morphine administered by cervical epidural catheter (CEC) on a model of thoracic limb pain. Study design Prospective, randomized, blinded crossover study. Animals Five adult horses.
Veronica L. Edwards   +3 more
wiley   +1 more source

The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis

open access: yesExperimental Physiology, EarlyView.
Abstract The present review aimed to investigate the effectiveness of aerobic exercise (AE) compared to other interventions in decreasing pain intensity and reducing disability in individuals with neck pain. A systematic review (SR) of randomized controlled trials was conducted. This SR was registered in PROSPERO (CRD42021231231).
Ana lzabela Sobral de Oliveira‐Souza   +9 more
wiley   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

Linking physical stimulation to molecular responses: The role and value of exosomes in mediating the systemic effects of Chinese Tuina

open access: yesClinical and Translational Discovery, Volume 6, Issue 2, April 2026.
(1) Tuina's mechanical forces activate cellular mechanosensors; (2) Induce multi‐tissue exosome release to mediate intercellular communication; (3) Exosomes systemically regulate muscle, nerve, immune and vascular functions; (4) Target gene knockout confirms exosomes’ specific mediating role.
Lifen Zhan   +4 more
wiley   +1 more source

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