Results 241 to 250 of about 143,881 (289)

Brazilian Society of Surgical Oncology: Guidelines and Consensus Statement for Palliative Surgery in Oncology

open access: yesJournal of Surgical Oncology, Volume 133, Issue 4, Page 421-432, March 15, 2026.
ABSTRACT Background and Objective Palliative surgery in oncology aims to relieve symptoms, improve quality of life, and respect patient autonomy in advanced cancer. This study aimed to develop evidence‐based recommendations for safely indicating and performing palliative surgeries in Brazil, considering clinical, ethical, and multidisciplinary aspects.
Audrey Cabral Ferreira de Oliveira   +15 more
wiley   +1 more source

Heart Failure: Epidemiology, Pathophysiology, and Management

open access: yesMedComm, Volume 7, Issue 3, March 2026.
This article takes calcium homeostasis as the point of departure to provide an overview of heart failure from three perspectives—epidemiology, pathophysiological mechanisms, and management strategies—and summarizes the current unmet needs and future directions in the field. ABSTRACT Heart failure (HF) is one of the leading causes of hospitalization and
Yujian Fan   +9 more
wiley   +1 more source

Peroxisome Proliferator‑Activated Receptor Gamma Coactivator‑1α Deficiency in Hippocampal Astrocytes Underlies Enhanced Fear Memory Retrieval in Male Posttraumatic Stress Disorder Model Mice

open access: yesMedComm, Volume 7, Issue 3, March 2026.
PGC‑1α downregulation in hippocampal astrocytes disrupts ATP release and reduces connexin 43 (CX43) expression, impairing neuro‑glial communication. This promotes enhanced fear memory retrieval in PTSD. Chemogenetic activation of astrocytes or PGC‑1α agonist treatment rescues both CX43 expression and fear behavior, identifying astrocytic PGC‑1α/CX43 as
Juan Wang   +6 more
wiley   +1 more source

A Holistic Wellness Prescription for Parkinson's Disease: Evidence‐Based Perspectives and Unmet Needs

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 3, Page 631-646, March 2026.
Abstract Background In modern medicine the concept of wellness is often accompanied by various misconceptions arising from several factors, including a lack of clear definitions, the commercialization of wellness, and prevailing biases and stereotypes.
Indu Subramanian   +40 more
wiley   +1 more source

Non-pharmacological approaches for migraine management: a mini-review. [PDF]

open access: yesFront Pain Res (Lausanne)
Singh V   +5 more
europepmc   +1 more source

Neuroinflammation‐Associated Optic Structural–Functional Degeneration in Early Diabetic Optic Neuropathy

open access: yesJournal of Diabetes, Volume 18, Issue 3, March 2026.
OCT imaging assessments and visual tests, which were validated by pyroptosis of retinal ganglion cells (RGC) and upregulation of NLRP3 and GSDMD expression, established an early structure‐function‐pathology diabetic optic neuropathy (DON) model in high glucose & obesity mice. Early retinal nerve fiber layer (RNFL)/total retinal thickness (TRT) thinning
Jingyuan Zhu   +3 more
wiley   +1 more source

Expert consensus on acupuncture for diabetic foot. [PDF]

open access: yesAm J Clin Exp Immunol
Tang X, Li G, Wang G, Chen S, Zhang L.
europepmc   +1 more source

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