Results 241 to 250 of about 4,919,156 (362)

Estimating the Cost and Carbon Output of Musculoskeletal Primary Care Management Decisions: A Retrospective Analysis of Electronic Health Records

open access: yesThe International Journal of Health Planning and Management, Volume 40, Issue 4, Page 907-922, July 2025.
ABSTRACT Background Healthcare accounts for up to 5% of worldwide carbon emissions and costs global economies an estimated $9 trillion annually. Primary care accounts for up to one‐fifth of all NHS carbon emissions, with musculoskeletal (MSK) pain accounting for 14%–30% of all primary care consultations.
Alex Braybrooke   +13 more
wiley   +1 more source

Laser acupuncture at BL20 Point Stimulate Pancreatic Beta cell in type 1 diabetes mellitus

open access: gold, 2019
Hartono Abdurachman   +2 more
openalex   +1 more source

Lactate Metabolism and Lactylation Modification: New Opportunities and Challenges in Cardiovascular Disease

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Lactate, beyond a metabolic byproduct, regulates immunity and inflammation, linked to cardiovascular diseases (CVD) via metabolic reprogramming. Lactylation, a lactate‐driven epigenetic mark, modulates gene expression in fibrosis, lipid disorders, and CVD progression.
Mengyang Song   +3 more
wiley   +1 more source

Association Between Stress Mindset, Work‐Related Stress and Burnout in Nursing Professionals: Empirical Research Quantitative

open access: yesNursing Open, Volume 12, Issue 7, July 2025.
ABSTRACT Aim To determine the relationship between stress mindset, work‐related stress and burnout in nursing professionals. We hypothesised that a stress‐is‐debilitating mindset is associated with higher work‐related stress and burnout levels. Design Cross‐sectional study.
Fernanda Carini Da Silva   +4 more
wiley   +1 more source

Experience and Needs of Immunotherapy for Lung Cancer Patients: A Meta‐Synthesis of Qualitative Studies

open access: yesPsycho-Oncology, Volume 34, Issue 7, July 2025.
ABSTRACT Objectives This study aimed to systematically evaluate the experience and needs of lung cancer patients undergoing immunotherapy, providing a theoretical basis for healthcare staff to implement comprehensive nursing programs for these patients.
Handan Zhang   +5 more
wiley   +1 more source

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

open access: yesSmall, Volume 21, Issue 26, July 3, 2025.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun   +12 more
wiley   +1 more source

Electroacupuncture Attenuates High‐Fat Diet‐Exacerbated Alzheimer's Pathology by Enhancing TFEB/TFE3‐Mediated Autophagic Clearance of Tau and NLRP3 Inflammasome in 3xTg Mice

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 7, July 2025.
Mechanistic model of EA‐ST36‐mediated reversal of HFD‐induced cognitive impairment in 3xTg‐AD mice through TFEB/TFE3 activation. The model illustrates that EA‐ST36 inhibits MTORC1 and activates TFEB/TFE3, enhancing the autophagy‐lysosomal pathway (ALP), which leads to the effective degradation of Tau aggregates and NLRP3 inflammasome components in the ...
Xiaoyan Zheng   +11 more
wiley   +1 more source

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