Results 171 to 180 of about 84,534 (351)

Considerations for Issues of Regression to the Mean and Contextual Effects in Clinical Trials for Pain in Rheumatic Diseases

open access: yesArthritis Care &Research, Volume 78, Issue 1, Page 31-37, January 2026.
Recently, there has been growing discussion about how to best assess pain in clinical trials in rheumatic diseases. Reliable measurement of pain outcomes is essential for accurately determining the effectiveness of treatments. Although pain intensity is the most common measure of change in pain trials, other pain‐related measures, such as pain ...
Yen T. Chen   +4 more
wiley   +1 more source

Natural Sweetener Stevioside‐Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 2, 14 January 2026.
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Junying Zhang   +7 more
wiley   +1 more source

Minimally Invasive Chemical Biopsy Needle with Self‐Wettable Extraction Phase For In Vivo Tissue Sampling During Medical Procedures

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
A new tissue sampling device using an acupuncture needle with bio‐compatible extraction sorbents in the recessed section is developed. The coating material using self‐wettable particles doesn't require solvent activation after sterilization. This device is applied for the anti‐cancer drug concentration monitoring during the in vivo lung perfusion ...
Runshan Will Jiang   +9 more
wiley   +1 more source

Studies of acupuncture therapy for chronic hepatic dysfunction.

open access: bronze, 1984
Yasuzo KURONO   +3 more
openalex   +2 more sources

TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
TNEA improves cognition in 5xFAD mice by modulating parvalbumin‐positive interneurons in hippocampal CA1. TNEA enhances gamma oscillations during rest and theta power during novel object recognition, restoring excitation/inhibition balance. These findings support TNEA as a minimally invasive therapy for Alzheimer's disease.
Zhongzhao Guo   +15 more
wiley   +1 more source

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