Results 21 to 30 of about 45,485 (213)

Layer‐Specific Dermal and Subcutaneous Delivery via Modular LNP–Hydrogel‐Integrated Threaded Microneedles

Advanced Science, EarlyView.
Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie, Yixiang Zhang, Shifeng Ling, Yuxuan Huang, Yingying Wei, Rao Fu, Jiahao He, Baikun Liu, Lucia Zhou, Kaifeng Huo, Yida Wang, Qingfeng Li, Yawei Du, Wenguo Cui, Yun Xie   +14 more
wiley   +1 more source

Achievements and Enlightenment of Modern Acupuncture Therapy for Stroke Based on the Neuroanatomy

针刺研究, 2014
Up to now,in the treatment of stroke patients by acupuncture therapy,three main representative achievements involving scalp acupuncture intervention,"Xing Nao Kai Qiao"(restoring consciousness and inducing resuscitation)acupuncture technique and nape ...
CHEN Li-fang, FANG Jian-qiao, CHEN Lu-ni, WANG Chao   +3 more
doaj   +2 more sources

Effect of Zuo's warming Yang acupuncture therapy combined with lifestyle interventions on prediabetes: A randomized controlled trial

Complementary Therapies in Medicine, 2023
Background: Acupuncture has promising effects on diabetes, but there is limited evidence on prediabetes. The purpose of this study was to evaluate the effect and safety of Zuo's warming Yang acupuncture therapy on prediabetic patients.
Yang Li, Kehang Xie, Xuanli Zeng, Lu Ding, Yuting Wang, Liming Lu, Changbo Zuo   +6 more
doaj   +1 more source

Hederagenin Attenuates Morphine Addiction via GABAA1‐Mediated Modulation of Ca2+–CaMK–CREB Signaling in Ventral Tegmental Dopaminergic Neurons

Advanced Science, EarlyView.
Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang, Ziting Zhou, Nannan Xue, Jiasi Deng, Yuanyuan Zhou, Xinying Lv, Yuxuan Wang, Yi Zhang, Haotian Pan, Geyan Xu, Yinkun Tao, Mengran Li, Xin Cui, Hongyue Ma, Qian Wang, Zhigang Lu   +15 more
wiley   +1 more source

Exploring Barrier-Free Esports for Visually Impaired and Sighted Individuals: An Examination of Rapid Key Tapping Speed

Disabilities
Esports involves competition conducted through online computer games, a format that allows individuals to compete together regardless of age, sex, or physique.
Miyono Okinaka, Tsunehiko Wada
doaj   +1 more source

Acupuncture Alleviates Allergic Rhinitis by Activating the AMPK/PGC‐1α Pathway to Attenuate Mitochondrial Oxidative Stress and Restore Epithelial Barrier Function

Flavour and Fragrance Journal, EarlyView.
Acupuncture at Feishu (BL13), Shenshu (BL23), Yingxiang (LI20), and Dazhui (GV14) alleviates allergic rhinitis by activating the AMPK/PGC‐1α/NRF1/TFAM signalling axis. This activation improves mitochondrial biogenesis and function, reduces mtROS‐mediated oxidative stress, restores ATP production and respiratory complex I/IV activity, suppresses IgE and
Fengying Zhang, Wei Meng, Renzhong Wang, Huijun Du   +3 more
wiley   +1 more source

Challenges in Menstrual Management Among Women with Visual Impairments: A Study of Riryouka Kyouin with Visual Impairments in Japan

Disabilities
This study aimed to clarify the menstrual experiences and perceptions of women with visual impairments in Japan. An anonymous web-based questionnaire consisting of both multiple-choice (quantitative) and open-ended (qualitative) questions was ...
Miyono Okinaka, Tsunehiko Wada
doaj   +1 more source

Progress in the Role of Mast Cells and Biomolecular Signals in the Mechanism of Postoperative Ileus: From Cellular Activation to Exploration of the Brain–Gut Axis

Gut Medicine, EarlyView.
ABSTRACT Postoperative ileus (POI) is a frequent complication after surgical procedures, predominantly manifesting as aberrant gastrointestinal motility, which markedly extends the duration of postoperative recovery for patients. The clinical duration of POI is typically modulated by intricate inflammatory cascades, with mast cells assuming a critical ...
Tian‐le Zhang, Miao‐ying Geng, Ming‐yue Shao, Gang Wang, Zhi‐wei Jiang   +4 more
wiley   +1 more source

Bridging Worlds: Can Evidence, Regulation and Indigenous Leadership Shape the Future of Traditional, Complementary and Integrative Medicine?

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Background and need As the WHO Global Traditional Medicine Strategy 2025–2034 encourages countries to consider integrating traditional, complementary and integrative medicine (TCIM) into health systems, there is a need to clarify the principal scientific, regulatory, ethical, and governance challenges involved. Renewed global attention to TCIM,
Abdul‐Basit Abdul‐Samed, Dina Balabanova, Neil Spicer, Martin McKee   +3 more
wiley   +1 more source

Augmentation effect of acupuncture on Bi’nao for hypophasis in patients with Bell’s palsy: study protocol for a randomized controlled trial

Trials, 2018
Background Hypophasis is one of the most frequently observed sequelae of patients with Bell’s palsy, who have not recovered completely, creating a clinical difficulty for physicians.
Xiaoyan Li, Chunlan Chen, Chuang Zhao, Zunyuan Li, Wei Liang, Zhidan Liu   +5 more
doaj   +1 more source