Results 111 to 120 of about 7,454,292 (340)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

24/7 TIA-service

open access: yesInternational Journal of Integrated Care, 2012
Although the symptoms of a transient ischemic attack (TIA) by definition resolve completely, the subsequent risk of cardiovascular complications is substantial. Urgent diagnosis and start of secondary prevention can reduce these risks.
Frank G van Rooij   +2 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Iron Deficiency Anemia: An Unexpected Cause of an Acute Occipital Lobe Stroke in an Otherwise Healthy Young Woman [PDF]

open access: yes, 2020
A 29-year-old caucasian woman who presented to the hospital with an acute onset of right eye visual disturbance and headache was found to have an acute left occipital lobe infarction.
Nace, Travis C   +3 more
core   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Virtual reality as an analgesic for acute and chronic pain in adults: a systematic review and meta-analysis

open access: yesJournal of Pain Research, 2019
Brian Mallari,1 Emily K Spaeth,2 Henry Goh,3 Benjamin S Boyd41Department of Physical Therapy, St. Mary’s Medical Center, San Francisco, CA, USA; 2Castro Valley Yoga, Castro Valley, CA, USA; 3Department of Physical Therapy, Kaiser Permanente ...
Mallari B, Spaeth EK, Goh H, Boyd BS
doaj  

Granulocytic Sarcoma of the Sciatic Nerve Manifested as Relapse of Acute Myeloid Leukemia: A Case Report

open access: yes대한영상의학회지, 2019
Granulocytic sarcoma is a form of extramedullary involvement of primitive myeloid cells. A 69-year-old male patient, with history of acute myeloid leukemia (AML) in remission state for 4 years, presented numbness, radiating pain and progressive motor ...
Seung Eun Lee   +3 more
doaj   +1 more source

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