Results 71 to 80 of about 6,769,906 (346)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Corrigendum: Vulnerable period in heart failure: a window of opportunity for the optimization of treatment – a statement by Mexican experts

open access: yesDrugs in Context
The authors wish to make the following corrections to their article: Magaña Serrano JA, Cigarroa López JA, Chávez Mendoza A, Ivey-Miranda JB, Mendoza Zavala GH, Olmos Domínguez L, Chávez Leal SA, Pombo Bartelt JE, Herrera-Garza EH, Mercado Leal G, Parra ...
José Antonio Magaña Serrano   +12 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

A Minor Historical Rule of GRAVE Concern in the Volta - Comoe Languages

open access: yesLegon Journal of the Humanities, 2014
The Volta-Comoe languages1 belonging to Greenberg's (1963) Niger-Congo undergo a historical change in which underlying labial /b/ is reflexed as velar [g] and labio-palatal [Ɉɥ] in their Central members and as [b] in their Eastern and Western subgroups ...
Lawrence Addai Boadi
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

A Randomized Controlled Trial of Early versus Late Surgical Decompression for Thoracic and Thoracolumbar Spinal Cord Injury in 73 Patients

open access: yesNeurotrauma Reports, 2020
Convincing clinical evidence exists to support early surgical decompression in the setting of cervical spinal cord injury (SCI). However, clinical evidence on the effect of early surgery in patients with thoracic and thoracolumbar (from T1 to L1 [T1?L1])
Ali Haghnegahdar   +16 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Pancreatitis aguda grave: curso clínico, manejo y factores asociados con mortalidad Severe acute pancreatitis: Clinical course, management, and mortality-associated factors

open access: yesRevista Colombiana de Cirugía, 2012
Objetivo. Describir el curso clínico de los pacientes con pancreatitis aguda en un centro hospitalario de cuarto nivel y explorar los factores de riesgo asociados con la mortalidad. Materiales y métodos.
Catalina Díaz   +3 more
doaj  

Molecular Targeting and Rational Chemotherapy in Acute Myeloid Leukemia

open access: yesJournal of Experimental Pharmacology, 2020
Fatemeh Pourrajab,1,2 Mohamad Reza Zare-Khormizi,3 Seyedhossein Hekmatimoghaddam,4,5 Azam Sadat Hashemi4,6 1Nutrition and Food Security Research Centre, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; 2Department of Clinical Biochemistry and ...
Pourrajab F   +3 more
doaj  

Microbiologic spectrum of acute and chronic dacryocystitis [PDF]

open access: yesInternational Journal of Ophthalmology, 2014
AIM:To report the microbiological spectrum of acute and chronic dacrocystitis.METHODS: Retrospective study on 100 patients who presented to the ophthalmic plastic clinic of a tertiary eye care center from May 2011 and April 2013 with acute and chronic ...
Bahram Eshraghi   +3 more
doaj   +1 more source

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