Results 201 to 210 of about 190,526 (265)

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Type 2 diabetes mellitus is associated with asymptomatic acute abdomen among elderly patients admitted to acute tertiary care hospital wards. [PDF]

Acta Diabetol
Tumminia A, Romano R, Frasca F, Galeano F, Baratta R, Oteri V, Longo A, Frittitta L, Le Moli R, Piticchio T, Di Pino A, Di Marco M, Piazza L, Picardo MC, Magnano San Lio P, Fimognari FL, Romano M.   +16 more
europepmc   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

Application of CPBL combined with mind mapping in acute abdomen clinical training to improve post-training competence. [PDF]

Front Med (Lausanne)
Xu ZW, Chen WD, Wang KQ, Zhao TL, Xu YC, Wang XY.   +5 more
europepmc   +1 more source

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Leiomyomatosis peritonealis disseminata presenting as acute abdomen: A rare case report. [PDF]

Int J Surg Case Rep
Gebreslase MN, Reta BK, Girmay HG, Zeray MA, Gebremariam AS.   +4 more
europepmc   +1 more source

Granulosa cell tumor patients presenting with acute abdomen: a case series. [PDF]

Gynecol Oncol Rep
Brink GJ, Groeneweg JW, Sickinghe AA, Lok CAR, Nijman HW, Piek JMJ, Hofhuis W, Roes EM, van Lonkhuijzen LRCW, de Kroon CD, Gort EH, Witteveen PO, Zweemer RP.   +12 more
europepmc   +1 more source

Gastric Volvulus, Pancreatic Volvulus, and Wandering Spleen: A Rare Emergency Triad Behind Acute Abdomen. [PDF]

Clin Case Rep
Layegh P, Mahdavi Rafie A, Doostparast A.   +2 more
europepmc   +1 more source

Unusual presentation of complicated relapsing fever with spontaneous hemoperitoneum mimicking surgical acute abdomen: a case report. [PDF]

Int J Emerg Med
Tesfay YG, Adera HK, Demissie ZG, Alemu DM, Mohammed MS, Hassen GW, Nuguse MK.   +6 more
europepmc   +1 more source