Results 71 to 80 of about 3,031,769 (377)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Machine learning-based integration of DCE-MRI radiomics for STAT3 expression prediction and survival stratification in breast cancer

Frontiers in Immunology
ObjectiveTo explore the association between signal transducer and activator of transcription 3 (STAT3) expression, tumor immune microenvironment, and overall survival (OS) in breast cancer, and to develop a non-invasive radiomics model for early risk ...
Dong Pan, Dong Pan, Dong Pan, Cheng-Yan Zhang, Cheng-Yan Zhang, Cheng-Yan Zhang, Ya-Fei Wang, Ya-Fei Wang, Shuang Liu, Shuang Liu, Shuang Liu, Xiong-Zhi Wu, Xiong-Zhi Wu, Xiong-Zhi Wu, Xiong-Zhi Wu, Xiong-Zhi Wu   +15 more
doaj   +1 more source

Presentación de caso para educación médica : abdomen agudo en paciente con diagnóstico de perforación intestinal por cuerpo extraño con resolución laparoscópica [PDF]

, 2017
Acute abdominal pain together with chest pain are the most common causes for people over 15 years of age to seek emergency medical attention. (Meyer, z et al., 2012). Between 1999 and 2008, visits to emergency services for acute abdomen increased by 31.8%
Wirth Rosales, Martín
core  

Clinicopathological Profile and Surgical Treatment of Abdominal Tuberculosis: A Single Centre Experience in Northwestern Tanzania. [PDF]

, 2013
Abdominal tuberculosis continues to be a major public health problem worldwide and poses diagnostic and therapeutic challenges to general surgeons practicing in resource-limited countries.
A Singhal, A Soylu, A Zafar, AU Arif, B Anuradha, BM Mawalla, C Bolukbas, E Akgun, EF Lyamuya, EHG Ahmed, FF Paustian, G Engin, H Ming-Luen, HS Shukla, HS Wang, Hyasinta Jaka, IA Khan, JE Gomez, JF Sharp, Joseph B Mabula, K Lonnroth, K Niaz, K-K Tan, KM Gondal, KR Palmer, L Werbeloff, M Akbar, M Saaiq, M Urassa, Mabula D Mchembe, Ministry of Health and Social Welfare, MJ Rajpoot, MP Sharma, MR Khan, MS Shaikh, MS Skopin, N Ali, N Wadhwa, NA Baloch, NV Addison, Peter F Rambau, Phillipo L Chalya, PJ Dolin, PJ Gupta, PJ Gupta, R Khan, RS Nyman, S Chandir, S Suri, SH Gondal, SM Khan, SP Misra, Stephen E Mshana, T Butt, T Iqbal, VK Kapoor, VK Kapoor, WP Homan   +57 more
core   +1 more source

Primary greater omental torsion as a cause of acute abdomen—a rare case report

Journal of Surgical Case Reports, 2018
Greater omental torsion is a rare entity that can cause acute abdominal pain, may mimick other abdominal pathologies, and is difficult to be diagnosed preoperatively. We present a case of a male patient with greater omental torsion mimicking the symptoms
M. Karanikas, K. Kofina, Ferdi Boz Ali, Vasileia Vamvakerou, Eleni Effraemidou, N. Lyratzopoulos, A. Polychronidis   +6 more
semanticscholar   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Acute pancreatitis risk in the diagnosis and management of inflammatory bowel disease: A critical focus

Open Medicine
We explored the causal relationship between pancreatitis and various autoimmune diseases using bidirectional Mendelian randomization (MR).
Zheng Feibo, Li Jinan, Ma Lina, Zhang Yu, Tu Zhengwei, Cui Yunfeng   +5 more
doaj   +1 more source

Acute Surgical Abdomen

Journal of Investigative Medicine High Impact Case Reports, 2014
Background . Pulmonary embolism is a common and potentially lethal condition. Most patients who die from massive pulmonary embolism do so within the first few hours of the event.
Nader AL-Mane LRCP & SI MB BCh NUI FCARCSI, Faisal AL-Mane MB BCh MRCPI FRCPC, Zein Abdalla MB BS MS FRCA, Joe McDonnell MB BCh FFARCSI   +3 more
doaj   +1 more source

Acute abdomen as a clinical presentation of lymphoma: A case report

Journal of Acute Disease, 2019
Rationale: Acute abdomen is a medical emergency that requires prompt diagnosis and management. Lymphoma is a rare cause of acute abdomen. Patient concerns: A 54 year old patient complained of repeated episodes of acute abdominal pain over the past 3 ...
Beuy Joob, Viroj Wiwanitkit
doaj   +1 more source

Early and late complications of bariatric operation. [PDF]

, 2018
Weight loss surgery is one of the fastest growing segments of the surgical discipline. As with all medical procedures, postoperative complications will occur. Acute care surgeons need to be familiar with the common problems and their management. Although
Beekley, Alec, Davis, Kimberly A., Johnson, Dirk C., Lim, Robert   +3 more
core   +1 more source