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Appendiceal microbiome in uncomplicated and complicated acute appendicitis: A prospective cohort study.

open access: yesPLoS ONE, 2022
BackgroundUncomplicated and complicated acute appendicitis seem to be two different forms of this common abdominal emergency. The contribution of appendiceal microbiota to appendicitis pathogenesis has been suggested, but differences between ...
Sanja Vanhatalo   +7 more
doaj   +3 more sources

Diagnosing acute appendicitis in children with neutrophil–lymphocyte ratio: a cross-sectional study [PDF]

open access: yesFrontiers in Pediatrics
BackgroundDiagnosing acute appendicitis (AA) in children can be challenging due to atypical symptoms and the difficulty in obtaining a comprehensive history. This study aimed to evaluate the value of the neutrophil-to-lymphocyte ratio (NLR) in diagnosing
Mohamed Mahmoud Shalaby   +4 more
doaj   +2 more sources

Acute Appendicitis [PDF]

open access: yesJAMA, 2021
“Science is built of facts the way a house is built of bricks: but an accumulation of facts is no more science than a pile of bricks is a house”, wrote the mathematician Henri Poincare. However, as surgeons and doctors, we have to face and consider our own “facts”. We are ageing! This is the first fact.
Mauro Podda   +7 more
  +5 more sources

Estimation of serum bilirubin level as a diagnostic laboratory marker of acute appendicitis and its role in prediction of appendicular perforation

open access: yesAsian Journal of Medical Sciences, 2023
Background: Acute appendicitis is the most common cause of surgical abdomen. A delay in diagnosis and subsequent delay in intervention may lead to appendicular perforation which leads to peritonitis and further complications including death.
Manoranjan Ghosh   +3 more
doaj   +1 more source

Nonoperative vs Operative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta-Analysis.

open access: yesJAMA Surgery, 2022
Importance Appendectomy remains the standard of care for uncomplicated acute appendicitis despite several randomized clinical trials pointing to the safety and efficacy of nonoperative management of this disease.
Rodrigo Moisés de Almeida Leite   +11 more
semanticscholar   +1 more source

Acute appendicitis in people living with HIV: What does the emergency surgeon needs to know?

open access: yesSAGE Open Medicine, 2021
Acute appendicitis is among the commonest surgical emergencies seen in an acute setting. Individuals living with the Human Immunodeficiency Virus (HIV) and/or the Acquired Immunodeficiency Syndrome (AIDS) have an increased risk of encountering ...
Arshad Mahmood   +4 more
doaj   +1 more source

Endoscopic retrograde appendicitis therapy versus laparoscopic appendectomy for uncomplicated acute appendicitis

open access: yesEndoscopy, 2022
Background and study aims: To assess the efficacy and clinical outcomes of endoscopic retrograde appendicitis therapy (ERAT) versus laparoscopic appendectomy (LA) for patients with uncomplicated acute appendicitis (AA).
Bao-Ren Yang   +9 more
semanticscholar   +1 more source

The microbiome in adult acute appendicitis

open access: yesGut Microbiome, 2022
Acute appendicitis is a common acute surgical emergency; however, the pathogenesis of adult appendicitis remains poorly understood. The microbiome is increasingly thought to play a key role in inflammatory disease of the bowel and similarly, may play a ...
Mei Sze Lee   +3 more
doaj   +1 more source

Effect of Oral Moxifloxacin vs Intravenous Ertapenem Plus Oral Levofloxacin for Treatment of Uncomplicated Acute Appendicitis: The APPAC II Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Antibiotics are an effective and safe alternative to appendectomy for managing uncomplicated acute appendicitis, but the optimal antibiotic regimen is not known.
S. Sippola   +21 more
semanticscholar   +1 more source

Non-operative management of acute appendicitis in children

open access: yesPediatric surgery international (Print), 2022
Appendicitis is one of the most common surgical emergencies in children and adults. Appendectomy as the standard care has been challenged in the recent years with growing evidence about non-operative treatment as a potential primary treatment in patients
Soma Jumah, T. Wester
semanticscholar   +1 more source

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