Results 51 to 60 of about 83,076 (281)

Safety, Tolerability, and Pharmacokinetics of the Long‐Acting SARS‐CoV‐2–Neutralizing Monoclonal Antibody Combination AZD7442 (Tixagevimab/Cilgavimab) in Healthy Chinese Adults

Clinical Pharmacology in Drug Development, EarlyView.
Abstract AZD7442, a combination of extended half‐life monoclonal antibodies tixagevimab and cilgavimab, was shown to neutralize previously circulating SARS‐CoV‐2 variants. This study evaluated safety, tolerability, pharmacokinetics, and pharmacodynamics of AZD7442 in healthy Chinese adults. In this randomized, placebo‐controlled, Phase 1 study, AZD7442
Nanyang Li, Jing Zhang, Wenhong Zhang, Zhongyuan Xu, Xiangcao Yao, Anqi He, Shuyuan Liu, Xiaoyun Ge, Jinxi Liu, Yunfei Li, Cecil Chi‐Keung Chen, Huixia Zhang   +11 more
wiley   +1 more source

Association of maternal biliary disease with hepatopancreatobiliary morbidity in offspring

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Maternal biliary disease is common, but the link with offspring hepatopancreatobiliary disease has not been studied. We assessed the association between maternal biliary disease and pediatric hepatopancreatobiliary morbidity. Methods We conducted a retrospective cohort study of 1,271,864 children born between 2006 and 2022 in Quebec,
Nathalie Auger, Angela Magri, Sarit Kang‐Auger, Gabrielle Jutras, Jessica Healy‐Profitós, Marianne Bilodeau‐Bertrand, Gabriel Côté‐Corriveau   +6 more
wiley   +1 more source

A Rare Complication of Acute Appendicitis: Superior Mesenteric Vein Thrombosis [PDF]

, 2016
Superior mesenteric vein (SMV) thrombosis caused by acute appendicitis is quite rare nowadays. These conditions occurs secondary to infection in the region drained by the portal venous system.
Johan, M. M. (Maisie), Koncoro, H. (Hendra), Setijoso, R. E. (Rafael)   +2 more
core   +3 more sources

Safety and Effectiveness of Cholecystectomy and Endoscopic Retrograde Cholangiopancreatography in Biliary Pancreatitis During Pregnancy: BORN Study

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Biliary acute pancreatitis (AP) during pregnancy is a challenging situation, and current guidelines for AP, pregnancy care, and surgery do not specifically address its management. This study investigated the safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography (ERCP) during pregnancy in AP ...
Dorottya Tarján, Eszter Ágnes Szalai, Bálint Erőss, Péter Jenő Hegyi, Vasile Liviu Drug, Serge Chooklin, Michael Hirth, Gabriel Sandblom, Vanessa Sandblom, Åsa Edergren, Ahmed Tlili, Sami Fendri, Simon Sirtl, Daniel de la Iglesia Gracía, Floreta Kurti, Dong Wu, Adriana Gherbon, Łukasz Nawacki, Alexandru Constantinescu, Natalia V. Shirinskaya, Alexander N. Zolotov, Sanjay Pandanaboyana, Tsukasa Ikeura, Tiago Cúrdia Gonçalves, Louise Rasmussen, Bodil Andersson, Ahmed Bouzid, Ahmed Saidani, Nándor Ács, Zoltán Sipos, Nelli Farkas, Balázs Tihanyi, Brigitta Teutsch, Johan Nilsson, Alexandra Mikó, Péter Hegyi   +35 more
wiley   +1 more source

Incidence of complicated acute appendicitis: a single-centre retrospective study

Studia Medyczne, 2017
Introduction : Abdominal pain has been one of the most common reasons patients seek medical care for centuries. Nowadays, together with laboratory diagnostics and imaging, we are able to make an early diagnosis.
Aneta Piotrowska, Sławomir Osman, Przemysław K. Wolak   +2 more
doaj   +1 more source

Balancing small against large burdens [PDF]

, 2018
Common principles for resource allocation in health care can prioritize the alleviation of small health burdens over lifesaving treatment. I argue that there is some evidence that these principles are at odds with a sizable share of public opinion, which
Voorhoeve, Alex
core   +3 more sources

Serious outcomes among emergency department patients with presyncope: A systematic review

Academic Emergency Medicine, EarlyView.
Abstract Background Syncope is transient loss of consciousness, and in presyncope, patients experience same prodromal symptoms without losing consciousness. While studies have extensively reported the risk of serious outcome among emergency department (ED) syncope, the outcome for patients with presyncope and their management are not well studied.
Hadi Mirfazaelian, Ian Stiell, Rasoul Masoomi, Khazar Garjani, Venkatesh Thiruganasambandamoorthy   +4 more
wiley   +1 more source

Appendicitis tends to be complicated during the COVID-19 epidemic: A multicentre retrospective study

Surgery Open Science
Background: In past studies, non-medical factors in the social-healthcare-patient triad associated with the prevalence of COVID-19 have led to delays in the presentation of patients with acute appendicitis and an increase in complications.
Macheng Lu, Xiangpeng Kong, Cong Cheng, Mengmeng Liu, Yuan Zhang, Qiuhua Zhang, Tong Wang, Ye Zhang, Huiqiang Dou   +8 more
doaj   +1 more source

The Relationship Between Diagnosis Of Acute Appendicitis And Leukocytosis Laboratory Results In The General Hospital Of Muhammadiyah Malang Period 2016-2017

Saintika Medika, 2020
In making the diagnosis in patients with symptoms that are not typical, the doctor needs to do a supporting examination, one of which is an examination of leukocytes count.
Mochamad Aleq Sander
doaj   +1 more source

Acute appendicitis in Ethiopia: A systematic review and meta-analysis

International Journal of Africa Nursing Sciences, 2021
Background: Acute appendicitis (AA) is the most common cause of acute inflammation in the right lower quadrant of the abdominal cavity and emergency abdominal surgery. In Ethiopia, the prevalence of acute appendicitis reported is variable.
Aynalem Adu, Yeneabat Birhanu
doaj   +1 more source