Results 101 to 110 of about 6,923,824 (296)

Induction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993 [PDF]

, 2005
The international acute lymphoblastic leukemia (ALL) study was designed to prospectively define the optimal therapy for adults 60 years of age or younger with newly diagnosed ALL.
Burnett, Alan Kenneth, Franklin, IM, Rowe, Jacob M., Richards, SM, Litzow, Mark R., Wiernik, P.H., Tallman, Martin S., Rowe, JM, Prentice, H. Grant, Goldstone, Anthony H., Wiernik, PH, Litzow, M.R., Litzow, MR, Ciobanu, N, Ciobanu, N., Prentice, HG, Durrant, J., Richards, Susan M., Durrant, J, Lazarus, H.M., Goldstone, A.H., Chopra, R, Lazarus, Hillard M., Wiernik, Peter H., Ciobanu, Niculae, Rowe, J.M., Tallman, MS, Durrant, Jill, Chopra, R., Lazarus, HM, Burnett, AK, Burnett, A.K., Buck, Georgina, Buck, G., Franklin, Ian M., Chopra, Raj, Goldstone, AH, Prentice, H.G., Richards, S.M., Tallman, M.S., Buck, G, Franklin, I.M., Chopra, Rajesh, Burnett, Alan K, Lazarus, Hillard M, Richards, Susan M, Wiernik, Peter H, Goldstone, Anthony H, Franklin, Ian M, Rowe, Jacob M, Durrant, I Jill, Tallman, Martin S, Litzow, Mark R, Prentice, H Grant   +53 more
core   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Membrane-Protecting Effects of Perfluorane on Red Blood Cells in Acute Blood Loss (an experimental study)

Общая реаниматология, 2011
Objective: to evaluate the membrane-protecting effect of perfluorane (PF) on red blood cells during hypotension and at the early stages of the postreinfusion period, by applying its various administration regimens. Materials and methods. Experiments were
V. V. Moroz, A. K. Kirsanova, I. S. Novoderzhkina, V. V. Aleksandrin, G. A. Nazarova   +4 more
doaj   +1 more source

Effects of dialysis modality on blood loss, bleeding complications and transfusion requirements in critically ill patients with dialysis-dependent acute renal failure.

, 2015
Blood loss and bleeding complications may often be observed in critically ill patients on renal replacement therapies (RRT). Here we investigate procedural (i.e.
Pschowski, R, Briegel, S, Pape, U F, Doehner, W, Schefold, Joerg C., Jörress, A, Hasper, D, Von Haehling, S, Bender, T O   +8 more
core  

Elevated pulse pressure during the acute period of ischemic stroke is associated with poor stroke outcome [PDF]

, 2004
<p><b>Background:</b> It is controversial which component of blood pressure (BP) during acute period of stroke best predicts outcome.
Lees, K.R., Aslanyan, S., Weir, C.J., ASLANYAN S, WEIR C. J, CAROLEI, ANTONIO, LEES K. R. FOR THE GAIN INTERNATIONAL STEERING COMMITTEE AND INVESTIGATORS   +6 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Significance of lipid peroxidation processes in renal excretory dysfunction in cases of acute blood loss complicated by limb ischemia-reperfusion and its correction

Journal of Education, Health and Sport, 2019
Introduction. Activation of lipid peroxidation processes, which are exacerbated in cases of limb ischemia-reperfusion associated with temporary application of a tourniquetis a key mechanism of acute blood loss.
V. V. Shatskyi, A. A. Hudyma
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

The role of mitral annular plane systolic excursion in prediction of acute blood loss in healthy voluntary blood donors. [PDF]

J Ultrason, 2022
Güllüpınar B, Sağlam C, Koran S, Turhan A, Ünlüer EE.   +4 more
europepmc   +1 more source

Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration [PDF]

, 2009
Background and Purpose—High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period.
Bath, P.M.B., M. Ali, Sare, Gillian M., Bath, Philip M.W., P. M.W. Bath, Sare, G.M., Ali, M., Shuaib, A., Ali, Myzoon, null null, Shuaib, Ashfaq, A. Shuaib, G. M. Sare   +12 more
core   +1 more source