Results 91 to 100 of about 73,824 (193)

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3819-3830, November 2026.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

Effects of EPs 7630 on the duration of inability to work in acute bronchitis - a meta-analysis. [PDF]

Multidiscip Respir Med, 2023
Matthys H, Funk P, Zimmermann A, Lehmacher W.   +3 more
europepmc   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 4003-4016, November 2026.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

An external validation study of a practical scoring system for identifying patients at risk of pelvic floor dysfunction following childbirth

International Journal of Gynecology &Obstetrics, Volume 175, Issue 2, Page 807-816, November 2026.
Abstract Objective To prospectively evaluate the perineal card, a risk‐based scoring system, for identifying women at increased risk of postpartum urinary incontinence (UI). Methods This prospective observational study included women without previous vaginal delivery who underwent vaginal birth at a tertiary referral center between June 2023 and ...
Martina Arcieri, Michela Segatti, Filippo Bordin, Doriana Armenise, Maria De Martino, Miriam Isola, Chiara Mattiussi, Elisa Barbui, Sara Filippin, Veronica Tius, Cristina Delneri, Valeria Dialti, Stefano Restaino, Lorenza Driul, Giuseppe Vizzielli   +14 more
wiley   +1 more source

Roles of Ambient Temperature and PM_2.5 on Childhood Acute Bronchitis and Bronchiolitis from Viral Infection. [PDF]

Viruses, 2022
Chen PC, Mou CH, Chen CW, Hsieh DPH, Tsai SP, Wei CC, Sung FC.   +6 more
europepmc   +1 more source

Probiotics as a Strategy for Mitigating Viral Infections in Poultry: Immunomodulatory Mechanisms and Therapeutic Potential

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Probiotics—particularly Lactobacillus acidophilus, L. casei and L. plantarum—may mitigate NDV, AIV and IBV infections by modulating immunity, supporting gut microbiome and barrier function, and enhancing vaccine responses, although stronger strain‐specific, safety, mechanistic and field‐based evidence is needed. ABSTRACT Poultry viral infections remain
Elmer Nayra Ametefe, Daniel Saka, Juliet Nuerkie Anang, Lourraine Sena Doh, Leonard Kofi Adjorlolo   +4 more
wiley   +1 more source

Antibiotic Stewardship in Patients With Acute Bronchitis: A Case Report of Doxycycline-Induced Esophagitis. [PDF]

Cureus, 2022
Butt MA, Peicher M, Nguyen AP, Sheikh AB.   +3 more
europepmc   +1 more source

Idiopathic immune‐mediated polyarthritis in a dog associated with ionised hypercalcaemia and probable ischaemic dermatopathy

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 5‐year‐old, spayed, female Shiba Inu was presented with a 6‐week history of reduced appetite, lethargy and generalised stiffness, which showed only limited improvement despite anti‐inflammatory treatment. The most significant clinical abnormalities were pyrexia, stiffness, pain on joint manipulation and cutaneous lesions. Laboratory findings
Jeanne Bergeat, Eddy Nassif, Sarah Berger, Isabelle Lagrange, Noëlle Cochet‐Faivre, Pierre Deshuillers, Maxime Kurtz   +6 more
wiley   +1 more source

Acute Bronchitis and Bronchiolitis Infection in Children with Asthma and Allergic Rhinitis: A Retrospective Cohort Study Based on 5,027,486 Children in Taiwan. [PDF]

Viruses, 2023
Sung FC, Wei CC, Muo CH, Tsai SP, Chen CW, Hsieh DPH, Chen PC, Lu CY.   +7 more
europepmc   +1 more source

Long‐term survival after surgical removal of an intermediate grade pancreatic carcinoma in a cat

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract An 11‐year‐old male neutered domestic shorthair cat presented with a history of acute diarrhoea, decreased appetite, and a palpable abdominal mass. Following clinical staging and histopathological examination after partial pancreatectomy, the cat was diagnosed with a completely excised intermediate grade pancreatic carcinoma without evidence ...
Abel Verbrugghe, Lynda Rutherford, Vicky Lipscomb, Simon Priestnall, Isabelle Desmas‐Bazelle   +4 more
wiley   +1 more source