Results 171 to 180 of about 3,076,930 (294)

Checkpoint‐Directed Glycoengineering Reprograms the Vascular Lumen for Siglec‐Mediated Immune Regulation

Advanced Science, EarlyView.
Checkpoint‐directed glycoengineering installs sialylated ligands on the donor vascular lumen during ex vivo preservation, creating a localized Siglec‐7/9‐engaging interface. The engineered glycocalyx suppresses immune‐cell activation, complement deposition, and microvascular injury in arterial and kidney allografts while preserving endothelial ...
Md Mohosin Rana, Javairia F. Rahim, Aaron P. Bernstein, Peyman Malek Mohammadi Nouri, Lyann Sim, Winnie Enns, Jenice M. Dumlao, Haiming D. Luo, Irina Chafeeva, Hong‐Ming Chen, Aizhou Wang, Jiao‐Jing Wang, Edward N. Schmidt, Zheng Jenny Zhang, Marcelo Cypel, Christopher Nguan, Matthew S. Macauley, Stephen G. Withers, Jonathan C. Choy, Jayachandran N. Kizhakkedathu   +19 more
wiley   +1 more source

When BAL meets CT scan: enhancing noninvasive diagnosis of acute cellular rejection after lung transplantation. [PDF]

BMC Pulm Med
Pordon E, Guerrieri M, Perillo F, Salvadori E, Fanetti M, Bergantini L, Ghiribelli C, Luzzi L, Catelli C, Bargagli E, Fossi A, Bellan C, Piscitello C, Mazzei MA, Bennett D.   +14 more
europepmc   +1 more source

Combining Serum miR-144-3p and miR-652-3p as Potential Biomarkers for the Early Diagnosis and Stratification of Acute Cellular Rejection in Heart Transplantation Patients. [PDF]

Transplantation, 2023
Pérez-Carrillo L, Sánchez-Lázaro I, Triviño JC, Feijóo-Bandín S, Lago F, González-Juanatey JR, Martínez-Dolz L, Portolés M, Tarazón E, Roselló-Lletí E.   +9 more
europepmc   +1 more source

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

Advanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir, Yagmur Ozendi, Gokhan Burcin Kubat, Keshav K. Singh   +3 more
wiley   +1 more source

The Role of Left Atrial Longitudinal Strain in the Diagnosis of Acute Cellular Rejection in Heart Transplant Recipients. [PDF]

J Clin Med, 2022
Rodríguez-Diego S, Ruiz-Ortiz M, Delgado-Ortega M, Kim J, Weinsaft JW, Sánchez-Fernández JJ, Ortega-Salas R, Carnero-Montoro L, Carrasco-Ávalos F, López-Aguilera J, López-Granados A, Arizón Del Prado JM, Romo-Peñas E, Pardo-González L, Hidalgo-Lesmes FJ, Álvarez-Ossorio MP, Mesa-Rubio D.   +16 more
europepmc   +1 more source

Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche

Advanced Science, EarlyView.
A subcutaneous synthetic immunological niche (IN) enables serial, minimally invasive monitoring of immune responses after islet transplantation. Flow cytometry and transcriptomic profiling of the IN reveal immune‐cell programs associated with graft acceptance and distinct types of rejection.
Jyotirmoy Roy, Abdalmonam Jadou Nejma, Mohammad Tarique, Amod Talekar, Shengli Wu, Brianna Ha, Yifei Jiang, Esma S. Yolcu, Lonnie D. Shea   +8 more
wiley   +1 more source

Impact of Era on Acute Cellular Rejection After Lung Transplantation. [PDF]

Transpl Int
Terada Y, Takahashi T, Pasque MK, Kulkarni HS, Vazquez-Guillamet R, Byers DE, Witt CA, Nava RG, Kozower BD, Meyers BF, Patterson GA, Kreisel D, Puri V, Hachem RR.   +13 more
europepmc   +1 more source

Tissue Expression of Programmed Cell Death 1 Ligand1 (PD-L1) in Biopsies of Transplant Livers of Pediatric Patients as a Possible Marker of Acute Cellular Rejection. [PDF]

J Clin Med, 2023
Szymanska S, Markiewicz-Kijewska M, Pyzlak M, Karkucinska-Wienckowska A, Ciopinski M, Czubkowski P, Kaliciński P.   +6 more
europepmc   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

Correlation between acute cellular rejection detected with cryobiopsy and elevated dd-cfDNA in lung transplant recipients. [PDF]

JHLT Open
Steinack C, Schuurmans MM, Vesenbeckh SM, Hage R, Rosselli Z, Ulrich S, Kohler M, Rüschoff J, Haberecker M, Roeder M, Gaisl T.   +10 more
europepmc   +1 more source