Results 51 to 60 of about 3,076,930 (294)

Electrical‐Programming‐Free Neural Crossbars Enabled by Photochemical Weight Patterning

Advanced Functional Materials, EarlyView.
A flexible neural‐crossbar hardware system enabled by electrical‐programming‐free, mask‐defined, array‐parallel photochemical weight patterning is demonstrated. Trained weights are physically implemented across the array, supporting multilevel programming, bending‐stable operation and reconfiguration, substrate reuse, and low‐energy readout while ...
Hyo‐Bin Jang, Ji‐Hoon Choi, Juhyung Seo, Seungwoo Baek, Hocheon Yoo, Hea‐Lim Park   +5 more
wiley   +1 more source

The Potential of MicroRNAs as Novel Biomarkers for Transplant Rejection

Journal of Immunology Research, 2017
The control of gene expression by microRNAs (miRNAs, miR) influences many cellular functions, including cellular differentiation, cell proliferation, cell development, and functional regulation of the immune system. Recently, miRNAs have been detected in
Matthias Hamdorf, Satoru Kawakita, Matthew Everly   +2 more
doaj   +1 more source

Molecular characterization of acute cellular rejection occurring during intentional immunosuppression withdrawal in liver transplantation.

, 2016
Acute cellular rejection occurs frequently during the first few weeks following liver transplantation. During this period, its molecular phenotype is confounded by peri- and postoperative proinflammatory events.
Lozano, J.J., Benítez, C., Bohne, F., Sanchez Fueyo, A., Martínez-Llordella, M., Bonaccorsi-Riani, E., Londoño, M.C., Sawitzki, B., Rimola, A., Sánchez-Fueyo, Alberto; id_orcid, Sánchez-Fueyo, A., Miquel, R., Bonacorssi-Riani, E., Martínez-Picola, M., Pennycuick, A., Londoño, M. C., Lozano, J. J., Martinez Llordella, M., Benítez, Carlos   +18 more
core   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Combination of anti-TNFα therapy and surgical resection for severe chronic intestinal rejection: A case report

Intestinal Failure
Background: Acute cellular rejection (ACR) is a well-recognised cause of graft failure in intestinal transplant (ITx) recipients. Management of ACR is with intravenous (IV) steroids, increased immunosuppression and T-cell depleting therapies.
Katrina Tan, Elizabeth Low, Graham Starkey, Khashayar Asadi, Adam Testro, Darren Wong   +5 more
doaj   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Unexplained Graft Dysfunction after Heart Transplantation—Role of Novel Molecular Expression Test Score and QTc-Interval: A Case Report

Cardiology Research and Practice, 2010
In the current era of immunosuppressive medications there is increased observed incidence of graft dysfunction in the absence of known histological criteria of rejection after heart transplantation.
Khurram Shahzad, Martin Cadeiras, Kotaro Arai, Dmitry Abramov, Elizabeth Burke, Mario C. Deng   +5 more
doaj   +1 more source

Acute Cellular Rejection and C4d Positivity in Heart Transplantation [PDF]

American Journal of Clinical Pathology, 2016
The role of routine C4d staining in endomyocardial biopsy specimens is uncertain. The implications of a diagnosis of acute cellular rejection (ACR) with a positive C4d with or without any evidence of antibody-mediated rejection (AMR) are unclear. This study sought to evaluate a distinct phenotype of ACR+/C4d+ in AMR- patients.Data on C4d, ACR, and AMR ...
Burhan, Mohamedali, Joseph, Pyle, Geetha, Bhat   +2 more
openaire   +2 more sources

When Poor Exciton Dissociation Limits Photocurrents in Organic Solar Cells: Why Low Offset Non‐Fullerene Acceptor Blends Can't Be Efficient

Advanced Materials, EarlyView.
The energetic offset between the donor and the acceptor components in organic photoactive layers is central to the tradeoff between photovoltage and photocurrent losses. This Perspective covers the most important issues surrounding this topic in non‐fullerene acceptor blends, from the difficulty of accurately determining state energies and driving ...
Dieter Neher, Manasi Pranav
wiley   +1 more source

LATE CELLULAR REJECTION IN PAEDIATRIC LIVER TRANSPLANTATION

, 2002
Background. Acute cellular rejection, though mostly encountered during the first 3 months after liver transplant, may occur later on. Clinical features and outcome of children experiencing late cellular rejection (LCR) have not been described to date ...
ANIL DHAWAN, Portmann, B, Rela, M, RUGGIERO FRANCAVILLA, NIGEL HEATON, Mieli-Vergani, G, MOHAMMED RELA, Francavilla, R, D'Antiga, L, LORENZO DʼANTIGA, Dhawan, A, Heaton, N, BERNARD PORTMANN, GIORGINA MIELI-VERGANI   +13 more
core   +1 more source