Results 81 to 90 of about 3,076,930 (294)

Prevalence of the Quilty effect in endomyocardial biopsy of patients after heart transplantation – from cellular rejection to antibody-mediated rejection? [PDF]

, 2016
The significance of the Quilty effect (QE) is not fully understood. It was once proposed to be related to acute cellular rejection (ACR). We aim to assess the relation between QE prevalence and antibody-mediated rejection (AMR).
Sylwia Szymanska, Wieslawa Grajkowska, Maciej Pronicki, Malgorzata Sobieszczanska-Malek, Michal Pyzlak, Tomasz Zielinski   +5 more
core   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Exploratory biomarkers for acute rejection in vascularized composite allotransplantation

Frontiers in Transplantation
Vascularized composite allotransplantation (VCA) involves immunologically heterogeneous tissues with a high incidence of acute rejection. Reliable and timely detection of rejection onset remains a major unmet challenge in VCA management.
Dominika Pullmann, William J. Rifkin, Haruyuki Hirayama, Bruce E. Gelb, Ata S. Moshiri, Massimo Mangiola, Eduardo D. Rodriguez, Catherine P. Lu, Catherine P. Lu, Piul S. Rabbani, Piul S. Rabbani   +10 more
doaj   +1 more source

Human herpesvirus-6 and cytomegalovirus DNA in liver donor biopsies and their correlation with HLA matches and acute cellular rejection

Brazilian Journal of Infectious Diseases, 2014
Herpesvirus reactivation is common after liver transplantation. Objective: Analyze the presence of cytomegalovirus (HCMV) and human herpesvirus-6 (HHV-6) DNA in liver donor biopsies, seeking to better understand issues involving human donor leukocyte ...
Ana Carolina Guardia, Raquel Silveira Bello Stucchi, Arlete Milan, Sandra Cecília Botelho Costa, Ilka de Fátima Santana Ferreira Boin   +4 more
doaj   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Clinical relevance and outcome of routine endomyocardial biopsy to detect rejection after heart transplantation

JHLT Open
Background: Endomyocardial biopsy has been the cornerstone of monitoring rejection after heart transplantation for decades. Although recommendations advise routine biopsies during the first 3-12 months, this timeframe is broad, and intercenter ...
Leendert C. Kieviet, BsC, Steven A. Muller, MD, Mariusz K. Szymanski, MD PhD, Manon G. van der Meer, MD PhD, M. Louis Handoko, MD PhD, Saskia Z.H. Rittersma, MD PhD, Saskia C.A. de Jager, Egidius E. van Aarnhem, MD PhD, Annelotte Vos, MD, Pim van der Harst, MD PhD, Linda W. van Laake, MD PhD, Marish I.F.J. Oerlemans, MD PHD   +11 more
doaj   +1 more source

Is monitoring of FOXP3 Treg cells in renal transplants during acute cellular rejection episodes useful?

, 2011
The FOXP3 (forkhead Box p3) transcription factor is a marker for T regulatory cells (Treg). During cellular immune responses, Treg are expected to increase in number to ultimately control and limit this response. In renal transplants massive infiltration
Hopfer, H., Gudat, F., Dickenmann, M., Dürmüller, U., Batsford, S., Mihatsch, M.   +5 more
core  

Incidence of rejection.

, 2016
The number of patient experiencing 1 or more biopsy proven rejections (including borderline cases with impaired renal graft function) according to the Banff 97 classification: 2 = antibody mediated rejection (AMR), 3 = borderline lesion, 4 I and 4 II ...
Michael Fischereder (784794), Jens Werner (135131), Ulf Schoenermarck (843167), Markus Guba (784795), Manfred Stangl (533575), Antje Habicht (367049), Teresa Kauke (843165), Sandra Klimaschewski (843166), Bruno Meiser (843169), Andrea Dick (843168)   +9 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Fibrosis Process Activation in Patients with Acute Cardiac Rejection: A Novel Noninvasive Diagnostic Approach

Biomedicines
Background/Objectives: Cardiac allograft fibrosis is an important limiting factor for long-term graft survival. However, the fibrotic process operating in patients with acute cellular rejection (ACR) remains unclear.
Marta Delgado-Arija, Lorena Pérez-Carrillo, Irene González-Torrent, Patricia Genovés, Isaac Giménez-Escamilla, Carlota Benedicto, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí   +9 more
doaj   +1 more source