Results 121 to 130 of about 1,592,264 (251)

Abdominal Pain as the First Presentation of Severe Heart Failure With Reduced Ejection Fraction and Left Ventricular Thrombus in a Young Asymptomatic Patient: A Diagnostic Interception

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A young, physically active patient with no cardiac symptoms presented with abdominal pain and was found, through incidental findings of elevated BNP, cardiomegaly, and new ECG changes, to have severe HFrEF with a left ventricular apical thrombus. Early cardiac evaluation changed management and led to complete thrombus resolution.
Maryam Othman Alarfaj, Bashayr Saleh Alsuwailem, Meataz Khaled Aljeezan, Baker Saud Alhlibi, Mubarak Maher Bu Haya, Abdulatif Adel Alnaaim, Muneera O. AlTaweel   +6 more
wiley   +1 more source

Disseminated Mixed Lytic‐Sclerotic Skeletal Metastases as Initial Presentation of Gallbladder Carcinoma: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Gallbladder carcinoma is an aggressive malignancy often diagnosed at an advanced stage. Skeletal metastasis, especially mixed lytic‐sclerotic lesions, is rare and typically occurs late. This report highlights an unusual presentation where widespread bony metastases were the initial manifestation, leading to the diagnosis of gallbladder ...
Shivali Rao, Binaya Adhikari, Abhikanta Khatiwada   +2 more
wiley   +1 more source

Complications of Acute Cholecystitis in Elderly Patients

, 2017
Acute cholecystitis is a pathological condition involving cholelithiasis with acute pain lasting 4 to 6 hours or clinical manifestation with prolonged biliary colic, accompanied by fever, laboratory evidence of inflammation or cholestasis.
Chaushev, D., Ivanov, T., Arnaudov, P., Stefanov, J., Chernopolsky, P., Plachkov, I., Lisnichkov, A., Madjov, R., Bozhkov, V., Georgiev, K.   +9 more
core   +1 more source

Weil's Syndrome Masquerading as Acute Cholangitis: A Case Report of a Farmer With Leptospirosis

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Leptospirosis can masquerade as acute cholangitis with cholestatic jaundice, fever, and leukocytosis. In febrile patients with cholestatic liver profile without biliary obstruction, especially farmers with calf pain and conjunctival suffusion, consider leptospirosis early to initiate timely antibiotics and prevent poor outcomes.
Ahmed Ali Shaikh, Fiza Shaikh, Saad Arshad, Tarachand Devrajani, Humayou Ahmed, Manal Al‐Dhaheri   +5 more
wiley   +1 more source

Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults

Clinical Pharmacology in Drug Development, Volume 15, Issue 10, October 2026.
Abstract REGN17092, a fully human immunoglobulin (Ig) G1 antibody with M252Y/S254T/T256E (YTE) modification in the Fc portion, was assessed in a first‐in‐human study (ClinicalTrials.gov, NCT05923424). REGN17092 was designed to target the severe acute respiratory coronavirus 2 (SARS‐CoV‐2) S protein.
Maria Rosario, Jan de Hoon, Flonza Isa, Kenneth Turner, Jing Li, Joel Kantrowitz, Samit Ganguly, Sasha Fraser, Zhongqing Will He, Hong Yan, Ana Gonzalez Ortiz, Lori Faria, Ingeborg Heirman, Alina Baum, Thomas D Norton, Yogesh Patel, Veronica Mas Casullo, John D Davis   +17 more
wiley   +1 more source

Gallstone formation and hepatobiliary tumour risk: Clinical implications of the bile acid–gut microbiota axis

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li, Yong Zhang, Kaishuang Cai, Shaojun Deng, Chaofeng Tan, Yunjie Li, Wenjin Liang   +6 more
wiley   +1 more source

Acute Acalculous Cholecystitis Associated with Hepatitis A Viral Infection: A Case Report

, 2023
Most hepatitis A infections are acute, self-limiting, and asymptomatic. In rare instances, extra hepatic complication, such as acute cholecystitis, may emerge.
Ariobimo, Bonfilio Neltio, Nujum, Nurun, Saputro, Daniel Ponco Harto   +2 more
core  

Evaluating the impact of an emergency department‐based advanced care unit on admission pathways and outcomes for geriatric patients with acute infection: A retrospective cohort study

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 5, October 2026.
Abstract Introduction The geographical separation of North Lantau Hospital (NLTH) from its tertiary referral centre, Princess Margaret Hospital (PMH), poses significant challenges for managing critically ill geriatric patients. An Emergency Medicine Advanced Care Unit (EMACU) was established in November 2020 to provide on‐site critical care. This study
Ying Ching Cynthia Wong, Tin Man Hui, Man Ting Lau, Oi Fung Wong, Shing Ko, Ka In Chan, Sau Lai Chan, Yu Tai Chan, Wai Kai Chan   +8 more
wiley   +1 more source

The Fibrosis‐4 Index Predicts Ceftriaxone‐Associated Gallstone Formation: Risk Stratification Using the Fibrosis‐4 Index in a Clinical Cohort

JGH Open, Volume 10, Issue 10, October 2026.
ABSTRACT Background Ceftriaxone is widely used because of its broad antimicrobial spectrum and convenient dosing; however, high biliary excretion can lead to calcium–ceftriaxone precipitation and gallstone‐like formations. Although exposure‐related risk factors have been described, the effect of hepatic fibrosis on ceftriaxone‐associated gallstone ...
Hideo Kato, Mao Hagihara, Hiroshige Mikamo, Takuya Iwamoto   +3 more
wiley   +1 more source

Prognostic parameters for the prediction of acute gangrenous cholecystitis

, 2006
Background/Purpose: The aim of this study was to identify preoperative prognostic parameters for gangrenous cholecystitis to differentiate this subgroup of patients with acute cholecystitis in order to provide immediate surgical therapy.
Kara, M., Titiz, I., Tekin, K., Altaca, G., Berber, I., Aydin, C.   +5 more
core   +1 more source