Results 51 to 60 of about 1,592,264 (251)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

A 52‐Week Efficacy and Safety Study of Teneligliptin, as an Add‐On to Empagliflozin and Metformin in Patients With Type 2 Diabetes Mellitus: A Randomised, Double‐Blind, Placebo‐Controlled Phase 3 Trial (TERA305 Study)

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the long‐term efficacy and safety of teneligliptin add‐on in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and empagliflozin. Materials and Methods In this randomised, double‐blind, phase 3 trial, 214 patients received teneligliptin 20 mg (n = 107) or placebo (n = 107) once daily for 24 ...
Jun Sung Moon, Kyung Ah Han, Dong‐Lim Kim, Sang Yong Kim, Soo‐Kyung Kim, Bon Jeong Ku, Woo Je Lee, Tae Keun Oh, Ji A Seo, Sang‐Ah Chang, Moon‐Kyu Lee, Kyu Jeung Ahn, Chul Sik Kim, Tae Nyun Kim, Bong‐Soo Cha   +14 more
wiley   +1 more source

A Case Report of Acute Acalculous Cholecystitis and Acute Hemorrhagic Cystitis due to Salmonella Typhi

Case Reports in Medicine, 2014
Acute acalculous cholecystitis and acute hemorrhagic cystitis due to Salmonella Typhi are a rare condition. A 24-year-old female patient was admitted to our clinic with abdominal pain, nausea, fever, headache, urinary burning, and bloody urine.
Hatice Beyazal Polat, Mehmet Beyazal, Fatma Beyazal Çeliker   +2 more
doaj   +1 more source

Predictive Models of Gangrenous Cholecystitis in Laparoscopic Cholecystectomy Treated Patients [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Gangrenous cholecystitis is difficult to diagnose clinically. There are no distinctive signs, symptoms or laboratory findings to distinguish it from acute cholecystitis.
Dhaval O Mangukiya, Keyur S Bhatt, Pankaj N Desai, Priya V Arora, Kaushal B Patel, Krishna K Parekh, Bhavin A Vyas   +6 more
doaj   +1 more source

Acute cholecystitis

Acta chirurgica Iugoslavica, 2003
Only 20 - 30% of patients with gallstones have symptoms and the probability of a patient with silent gallstones developing biliary-related pain is 1- 2% while the risk of developing a serious complication (e.g. empyema, perforation, peritonitis etc.) is less than 0.1% per year.
openaire   +3 more sources

Biliary Abnormality on Imaging During Lenvatinib Plus Hepatic Arterial Infusion Chemotherapy With Cisplatin for Hepatocellular Carcinoma: A Pilot Descriptive Study

Hepatology Research, EarlyView.
ABSTRACT Aim To evaluate the frequency, imaging characteristics, associated factors, and clinical significance of biliary abnormalities on imaging in patients receiving lenvatinib (LEN) plus cisplatin hepatic arterial infusion chemotherapy (HAIC) for hepatocellular carcinoma (HCC).
Hirohito Osanai, Kazuto Kozaka, Takashi Matsubara, Norihide Yoneda, Takahiro Ogi, Kenichiro Okumura, Atsushi Takamatsu, Azusa Kitao, Shintaro Yagi, Taro Yamashita, Satoshi Kobayashi   +10 more
wiley   +1 more source

Patients', Relatives' and Healthcare Professionals' Experiences and Perceptions of Raising Concerns About Acute Deterioration: A Qualitative Case Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore adult patients', relatives', and healthcare professionals' experiences of acute deterioration and perceptions of patient/family involvement in raising concerns. Design A collective case study underpinned by implementation science.
Aidín McKinney, Donna Fitzsimons, Bronagh Blackwood, Jennifer McGaughey   +3 more
wiley   +1 more source

Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention

ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou, Yu Wu, Guoran Li, Yongwen Qin, Man Qi, Zhitao Jin   +5 more
wiley   +1 more source

Exploring Long‐Term Outcomes in Sepsis Survivors: A Prospective Cohort Study Across Acute Hospitals

Journal of Advanced Nursing, EarlyView.
ABSTRACT Introduction While sepsis survival rates have improved, long‐term consequences remain under‐recognised and support services limited. Survivors often face persistent physical, cognitive and psychological impairments that diminish their quality of life.
Katie O'Byrne, Anne‐Marie Brady, Eileen Whelan, Claire Foley, Elaine Harris, Christina Lydon, Fiona Moore, Rynagh Gilligan, Vida Hamilton, Karn Cliffe   +9 more
wiley   +1 more source

OUTCOMES OF LAPAROSCOPIC CHOLECYSTECTOMY IN ACUTE CHOLECYSTITIS

Pakistan Armed Forces Medical Journal, 2018
Objective: To study the morbidity and mortality of early laparoscopic cholecystectomy in acute cholecystitis by comparing its results with laparoscopic cholecystectomy in chronic cholecystitis and simple cholelithiasis.
Shafqat Rehman, Muhammad Afzal, Muhammad Qasim But   +2 more
doaj   +2 more sources