ABSTRACT Aims To evaluate the bioequivalence of orally administered orforglipron tablets and capsules in participants with obesity or overweight who were otherwise healthy. Materials and Methods This phase 1, multicenter, open‐label, multiple‐dose, dose‐escalation study was conducted in 429 healthy adults.
Xiaosu Ma +5 more
wiley +1 more source
Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention
ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou +5 more
wiley +1 more source
Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies
ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara +3 more
wiley +1 more source
RISK OF CONVERSION OF OPERATIONAL INTERVENTION IN ACUTE CHOLECYSTITIS, COMPLICATED BY PERITONITIS
Calculous acute cholecystitis, in emergency abdominal surgery, is ranked second after acute appendicitis. A scientific study was undertaken regarding the effectiveness and the priorities of the active involvement tactics in the treatment of these ...
Boris Zaporozhchenko +4 more
doaj
Cost-Effectiveness Analysis of Endoscopic Ultrasound versus Magnetic Resonance Cholangiopancreatography in Patients with Suspected Common Bile Duct Stones. [PDF]
Patients with suspected common bile duct (CBD) stones are often diagnosed using endoscopic retrograde cholangiopancreatography (ERCP), an invasive procedure with risk of significant complications.
Davidson, BR +3 more
core +3 more sources
Acute acalculous cholecystitis in systemic lupus erythematosus: a rare initial manifestation
Acute acalculous cholecystitis is a very rare gastrointestinal manifestation in systemic lupus erythematosus and becomes rarer as an initial manifestation. There are only two cases reported.
Valdano Manuel +3 more
doaj +1 more source
A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel. [PDF]
Pexidartinib (PLX3397) is a small molecule tyrosine kinase and colony-stimulating factor-1 inhibitor with FDA breakthrough therapy designation for tenosynovial giant-cell tumor, and currently under study in several other tumor types, including breast ...
Chien, A Jo +5 more
core
ABSTRACT We hereby report a case of a 75‐year‐old patient who developed a large left‐sided hemopneumothorax after a routine dual‐chamber pacemaker insertion. The rare complication was caused by the pacing lead injuring the left internal mammary artery (LIMA) after perforating the right ventricle.
Stuart Stenton +3 more
wiley +1 more source
Comparative Evaluation of Laparoscopic Cholecystectomy in Acute and Chronic Cholecystectomy
BACKGROUND AND OBJECTIVE: Laparoscopic cholecystectomy has been performed for the management of hepatobiliary diseases. Early laparoscopic cholecystectomy (LC) was contraindication for acute cholecystitis (AC).
AA Darzi, +6 more
doaj
Chronic Cholecystitis with Synchronized Candida Infection – A Rare Case from Rural India
Background. Candida infection may cause acute, necrotizing or suppurative cholecystitis. Acute cholecystitis with Candida infection has been reported in patients with malignancies.
Dayal S.
doaj +1 more source

