Results 91 to 100 of about 2,625,804 (282)

Exercise-Induced Paraspinal Muscle Rhabdomyolysis with Seconary Compartment Syndrome: A Case Report

대한영상의학회지, 2019
Lumbar paraspinal compartment syndrome is an uncommon cause of acute lower back pain. It can result from intense physical activity or as a complication of surgery or medication.
Soong Moon Cho, Ghi Jai Lee, Yong Jun Jin, Ki Hwan Kim, Kyoung Eun Lee, Jae-Chan Shim, Dae Hyun Hwang, Ho Kyun Kim   +7 more
doaj   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Common adverse events associated with the use of ribavirin for severe acute respiratory syndrome in Canada [PDF]

, 2003
Although information on efficacy and adverse drug reactions is lacking, ribavirin has been used empirically for the treatment of severe acute respiratory syndrome (SARS). We report common adverse events in 110 patients with suspected or probable SARS who
Dresser, L., Linda Dresser, Larissa Matukas, Elizabeth J. Phillips, Phillips, E.J., Matukas, L., Sandra R. Knowles, Knowles, S.R.   +7 more
core   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Evaluation of acute compartment syndrome of extremities in emergency room: a case series of 32 children [PDF]

, 2015
The aim of this study was to analyze the clinical signs of diagnosis, treatment and followupof the pediatric population presenting with acute compartment syndrome in theemergency room at an Institutional Level II trauma center. The study is a prospective
Srivastava, RN, Singh, A, Ali, S
core   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Acute lower extremity compartment syndrome secondary to gabapentin-induced rhabdomyolysis: A case report

Foot & Ankle Surgery: Techniques, Reports & Cases
Drug-induced compartment syndrome is a rare, limb- and life-threatening condition. This etiology of compartment syndrome can often be distinguished from other causes by the presence of severe rhabdomyolysis.
Patrick Kagel, DPM, Varsha Atuluru, DPM, Timothy Hoffmeister, DPM, Paul Carroll, DPM, FACFAS   +3 more
doaj   +1 more source

Abstracts of Symposium II: Acute Coronary Syndrome: The Obstructive Plug

, 2018
s of Symposium II: Acute Coronary Syndrome: The Obstructive ...
Acute Coronary Syndrome: The Obstructive Plug, Symposium II:
core   +1 more source

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

Using Near-Infrared Spectroscopy Monitoring to Diagnose Acute Compartment Syndrome [PDF]

Acute compartment syndrome is a condition of increased pressure in injured extremities leading to decreased oxygen delivery and tissue death in the limb. This condition requires prompt diagnosis to avoid complications such as muscle death and amputation.
Yanez, Andres
core   +1 more source