Results 41 to 50 of about 155,674 (294)

Intra-abdominal hypertension and abdominal compartment syndrome in pancreatitis, paediatrics, and trauma [PDF]

, 2015
Intra-abdominal hypertension (IAH) is an important contributor to early organ dysfunction in trauma and sepsis. However, relatively little is known about the impact of intra-abdominal pressure (IAP) in general internal medicine, pregnant patients, and ...
De Keulenaer, Bart L, De laet, Inneke, De Waele, Jan, Ejike, Janeth C, Ivatury, Rao, Kimball, Edward, Kirkpatrick, Andrew W, Leppäniemi, Ari, Malbrain, Manu LNG, Roberts, Derek J   +9 more
core   +1 more source

The GATA1s isoform is normally down-regulated during terminal haematopoietic differentiation and over-expression leads to failure to repress MYB, CCND2 and SKI during erythroid differentiation of K562 cells [PDF]

, 2012
Background: Although GATA1 is one of the most extensively studied haematopoietic transcription factors little is currently known about the physiological functions of its naturally occurring isoforms GATA1s and GATA1FL in humans—particularly whether the ...
A Quintas-Cardama, A Zipursky, AG Muntean, AG Muntean, Brenda Gibson, C Halsey, C Kuhl, Christina Halsey, CS McKimmie, Derek Gilchrist, Gerard Graham, H Sakamoto, I Matsumura, J Wechsler, JD Crispino, JP Bourquin, K Georgopoulos, KA Alford, L Gutierrez, LC Andersson, LM Hollanda, M Ritter, Marie Docherty, ME Greene, Mhairi McNeill, Michelle Le Brocq, N Shimokawa, N Suzuki, N Ueki, O Tunstall-Pedoe, PA Tetteroo, R Alitalo, R Calligaris, R Ferreira, RA Shivdasani, S Pearson-White, S Teichler, T Nomura, Y Ge, Z Li   +39 more
core   +2 more sources

Acute Isolated Thenar Compartment Syndrome in a Patient with Evans Syndrome: A Case Report

Clinical Practice and Cases in Emergency Medicine, 2022
Introduction: Acute compartment syndrome of the hand is a rare medical emergency, most often associated with trauma or fracture. Case Report: Here, we describe a rare case of isolated thenar compartment syndrome of the hand in the absence of major trauma
Elisabeth Jiang, Kevin H. Kim, Alan Babigian   +2 more
doaj   +1 more source

Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]

, 2013
Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico, Carpino, G, Franchitto, Antonio, Gaudio, Eugenio, Mancinelli, Romina, Onori, Paolo, Renzi, Anastasia   +6 more
core   +1 more source

Clinical and radiographic predictors of acute compartment syndrome in the treatment of tibial plateau fractures: a retrospective cohort study

BMC Musculoskeletal Disorders, 2017
Background The aim of the study was to evaluate the relation between demographic, injury-related, clinical and radiological factors of patients with tibial plateau fractures and the development of acute compartment syndrome. Methods All consecutive adult
Axel Gamulin, Anne Lübbeke, Patrick Belinga, Pierre Hoffmeyer, Thomas V. Perneger, Matthieu Zingg, Gregory Cunningham   +6 more
doaj   +1 more source

Leukocyte sequestration in pulmonary microvessels and lung injury following systemic complement activation in rabbits [PDF]

, 1999
Inflammatory reactions are associated with sequestration of leukocytes in the lung. Complement activation leads to accumulation of leukocytes in alveolar septa and alveoli, to lung edema and hemorrhage.
Goetz, Alwin Eduard, Groh, Joachim, Kiefmann, Rainer, Kuebler, Wolfgang M., Kuhnle, Gerhard E. H., Sckell, Axel   +5 more
core   +1 more source

Ezetimibe therapy: mechanism of action and clinical update. [PDF]

, 2012
The lowering of low-density lipoprotein cholesterol (LDL-C) is the primary target of therapy in the primary and secondary prevention of cardiovascular events.
Dayspring, Thomas D, Phan, Binh An P, Toth, Peter P   +2 more
core   +1 more source

Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock [PDF]

, 2005
Stress doses of hydrocortisone a re known to have immunomodulatory effects in patients with hyperdynamic septic shock. The prognosis correlates with the presence and severity of septic encephalopathy. However, neurological evaluation is influenced by the
Anderson, Annane, Astudillo, Barie, Barie, Bastos, Bertsch, Blomquist, Bollaert, Bolton, Bolton, Bone, Briegel, Briegel, Briegel, Briegel, Danielson, Donato, Eidelman, Endo, Haimoto, Herrmann, Hollenberg, Hund, Hund, Jonsson, Keh, Lindner, Marshall, Metinko, Munck, Mussack, Mussack, Pelinka, Pelinka, Rosen, Schwarz, Stanimirovic, Usui, Vincent, Waage, Weiss, Westaby, Wheeler, Wiesmann, Wunderlich, Young   +46 more
core   +2 more sources

Awareness and knowledge of intra-abdominal hypertension and abdominal compartment syndrome: results of an international survey [PDF]

, 2014
Background: Surveys have demonstrated a lack of physician awareness of intra-abdominal hypertension and abdominal compartment syndrome (IAH/ACS) and wide variations in the management of these conditions, with many intensive care units (ICUs) reporting ...
De Keulenaer, Bart L, De laet, Inneke, De Waele, Jan, Debergh, Dieter, Kirkpatrick, Andrew W, Malbrain, Manu LNG, Roberts, Derek J, Vandervelden, Stefanie, Wise, Robert   +8 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source