Results 101 to 110 of about 469,048 (336)

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

Diagnosis and Prognostic Value of the Underlying Cause of Acute Coronary Syndrome in Optical Coherence Tomography–Guided Emergency Percutaneous Coronary Intervention [PDF]

, 2023
Seita Kondo, Takuya Mizukami, Nobuaki Kobayashi, Kohei Wakabayashi, Hiroyoshi Mori, Myong Hwa Yamamoto, Takehiko Sambe, Sakiko Yasuhara, Kiyoshi Hibi, Mamoru Nanasato, Tomoyo Sugiyama, Tsunekazu Kakuta, Takeshi Kondo, Satoru Mitomo, Sunao Nakamura, Masamichi Takano, Taishi Yonetsu, Takashi Ashikaga, Tomotaka Dohi, Hirosada Yamamoto, Ken Kozuma, Jun Yamashita, Junichi Yamaguchi, Hiroshi Ohira, Kaneto Mitsumata, Atsuo Namiki, Shigeki Kimura, Junko Honye, Nozomi Kotoku, Takumi Higuma, Makoto Natsumeda, Yuji Ikari, Teruo Sekimoto, Hidenari Matsumoto, Hiroshi Suzuki, Hiromasa Otake, Yoichiro Sugizaki, Naoei Isomura, Masahiko Ochiai, Satoru Suwa, Toshiro Shinke, TACTICS investigators   +41 more
openalex   +1 more source

Spontaneous Coronary Artery Dissection: A Case Series of 9 Patients With Literature Review. [PDF]

, 2018
Spontaneous coronary artery dissection is an increasingly recognized nonatherosclerotic cause of acute coronary syndrome. Reports regarding the prognosis and natural history of this disease are limited.
Ali, Nouman Safdar, Anjum, Reema, Ghani, MD, Ali Raza, Hashmi, Arsalan Talib, Inayat, Faisal, Klugherz, Bruce D., Riaz, Iqra, Viray, Michael, Virk, Hafeez Ul Hassan   +8 more
core   +2 more sources

Machine learning methods for predicting adverse drug events: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo, Fatemeh Ahmadi, Mohammad Ali Omrani, Sheikh S. Abdullah, Neda Rostamzadeh, Atefeh Jafari, Lujain Izzedin, Kamran Sedig, Flory T. Muanda   +8 more
wiley   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

Hepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers   +4 more
wiley   +1 more source

Acute coronary syndrome: pathogenesis, diagnosis, treatment, rehabilitation (part 1)

КардиоСоматика, 2016
The lecture provides a definition of "acute coronary syndrome" and entities that united this term. The mechanisms of the development and clinical manifestation of acute coronary syndrome.
N. B Perepech
doaj  

Kounis Syndrome Associated With Selective Anaphylaxis to Cefazolin. [PDF]

, 2018
info:eu-repo/semantics ...
Chambel, M, Correia, M, Gaspar, A, Morais-Almeida, M, Mota, I, Sequeira, T   +5 more
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Factors associated with cardiovascular events after simultaneous liver–kidney transplant from the US Multicenter Simultaneous Liver–Kidney Transplant Consortium

Hepatology Communications, EarlyView., 2022
Abstract Cardiovascular disease is a leading complication after both liver and kidney transplantation. Factors associated with and rates of cardiovascular events (CVEs) after simultaneous liver–kidney transplant (SLKT) are unknown. This was a retrospective cohort study of adult SLKT recipients between 2002 and 2017 at six centers in six United Network ...
Jennifer Jo, Gonzalo Crespo, Dyanna Gregory, Jasmine Sinha, Jiaheng Xie, Min Zhang, John Magee, Pranab Barman, Yuval A. Patel, Aaron Schluger, Kara Walters, Scott Biggins, Natalia Filipek, Giuseppe Cullaro, Randi Wong, Jennifer C. Lai, Gabriel J. Perreault, Elizabeth C. Verna, Pratima Sharma, Lisa B. VanWagner   +19 more
wiley   +1 more source

Cessation of dual antiplatelet therapy and cardiovascular events following acute coronary syndrome [PDF]

, 2019
Objective: To assess whether cardiovascular events are increased after cessation of dual antiplatelet therapy (DAPT) following acute coronary syndrome (ACS) and to explore predictors for recurrent events after DAPT cessation during long-term follow-up.
Berry, Colin, Dawson, Jesse, Mazlan-Kepli, Wardati, Walters, Matthew   +3 more
core   +1 more source