Results 61 to 70 of about 276,079 (291)

Pathogenesis of Acute Coronary Syndromes

Journal of the American College of Cardiology, 2013
Experimental models of atherogenesis have provided a growing body of information about molecular mechanisms of plaque growth; however, transition from coronary stability to instability is less well understood due to the lack of animal models reflective of human disease.
Crea, Filippo, Liuzzo, Giovanna
openaire   +3 more sources

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Acute Coronary Syndrome in Pregnancy

Clinical Medicine Insights: Cardiology, 2009
Acute coronary syndrome (ACS) in pregnancy has traditionally been considered to be a rare event, but the combination of normal physiological changes of pregnancy and more prevalent cardiovascular risk factors are increasing its incidence in this ...
Douglas Wright, Claire Kenny-Scherber, Alison Montgomery, Omid Salehian   +3 more
doaj  

Rationale, design and methodology of a double-blind, randomized, placebo-controlled study of escitalopram in prevention of Depression in Acute Coronary Syndrome (DECARD)

Trials, 2009
Background The prevalence of depression in patients with acute coronary syndrome, i.e. myocardial infarction and unstable angina, is higher than in the general population. The prevalence of anxiety is higher as well.
Hansen Jørgen, Rasmussen Alice, Hanash Jamal, Hansen Baiba, Birket-Smith Morten   +4 more
doaj   +1 more source

Perivascular fat attenuation index measured by coronary computed tomography angiography as a tool for assessment of ischaemia-causing lesions: a case report

BMC Cardiovascular Disorders, 2023
Background It can be difficult to diagnose coronary artery disease in patients with acute coronary syndrome if coronary angiography does not identify stenosis. Coronary inflammation, which can contribute to the pathogenesis of coronary artery disease and
Shuichi Okamoto, Junji Mochizuki, Hiroaki Matsumi, Katsushi Hashimoto, Akira Nikaido, Yoshiki Hata   +5 more
doaj   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

Acute Coronary Syndrome in an Intensive Care Unit of a Tertiary Referral Centre in Central Nepal: The Spectrum and Coronary Risk Factors.

Journal of Nepal Medical Association, 2013
Introduction: Acute coronary syndrome is the major leading cause for coronary care unit admission. Its spectrum comprises a variety of disorders including unstable angina, non ST elevation and ST elevation myocardial infarction.
Mani Prasad Gautam, Guruprasad Sogunuru, Gangapatnam Subramanyam, Lekhjung Thapa, Raju Paudel, Madhav Ghimire, Gautam Samir, Usha Ghimire, Ramila Shilpakar   +8 more
doaj   +3 more sources

Biomarkers in Acute Coronary Syndrome

Biomarker Insights, 2008
Background: Evaluation of patients who present to the hospital with acute undifferentiated chest pain or other symptoms and signs suggestive of Acute Coronary Syndrome (ACS) is often a clinical challenge.The initial assessment, requiring a focused ...
Valentina Loria, Milena Leo, Gina Biasillo, Ilaria Dato, Luigi M. Biasucci   +4 more
doaj  

Risk factors of delayed pre-hospital treatment seeking in patients with acute coronary syndrome: A prospective study

Turkish Journal of Emergency Medicine, 2015
Objectives: Despite enormous efforts in public education, treatment seeking time still remains more than optimal in patients with acute coronary syndrome.
Marzieh Fathi, Aysan Rahiminiya, Mohammad Amin Zare, Nader Tavakoli   +3 more
doaj   +1 more source

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen, Wei Liu, Dan Zhou, Shuhua Liu, Yalun Guan, Zongyu Miao, Lei Cai, Xuejiao Li, Yunfeng Li, Zhongqiang Huang, Yi Jin, Ge Li, Yu Zhang   +12 more
wiley   +1 more source