Results 41 to 50 of about 174,648 (315)
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin +6 more
wiley +1 more source
Prognostic value of troponins in acute coronary syndrome depends upon patient age [PDF]
Peer ...
Bachmann, M. O. +5 more
core +1 more source
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler +8 more
wiley +1 more source
Automatic covariate selection in logistic models for chest pain diagnosis: A new approach [PDF]
A newly established method for optimizing logistic models via a minorization-majorization procedure is applied to the problem of diagnosing acute coronary syndromes (ACS).
Baxt +39 more
core +1 more source
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
Tight Glycemic control in acute coronary syndromes: Prognostic implications
Background: Elevated admission plasma glucose is associated with increased mortality in patients who are admitted with acute coronary syndromes. Aim: To validate the hypothesis that tight glycemic control could reduce major adverse cardiac events in ...
Reham El-Shenawy +3 more
doaj +1 more source
Access and non–access site bleeding after percutaneous coronary intervention and risk of subsequent mortality and major adverse cardiovascular events:Systematic review and meta-analysis [PDF]
Background: The prognostic impact of site-specific major bleeding complications after percutaneous coronary intervention (PCI) has yielded conflicting data.
Buchan, Iain +10 more
core +1 more source
Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour +11 more
wiley +1 more source
Clinical Use and Measurement of Cardiac Troponin (cTn)
Cardiac troponins are cardio-specific and are widely used for the early diagnosis and triage of patients with acute coronary syndromes in conjunction with clinical history, electrocardiographic changes and imaging.
Clementine YF Yap MSc, DLM (ASCP) +2 more
doaj +1 more source
A comprehensive approach to the diagnosis and treatment of chronic coronary syndrome [PDF]
Coronary artery disease (CAD) is a chronic progressive disease with social signifi cance, result ofobstructive or non- obstructive atherosclerotic plaque accumulation in the epicardial arteries.
Velina Stoyanova
doaj +3 more sources

