Results 41 to 50 of about 174,648 (315)

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

Prognostic value of troponins in acute coronary syndrome depends upon patient age [PDF]

open access: yes, 2014
Peer ...
Bachmann, M. O.   +5 more
core   +1 more source

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

open access: yesArthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler   +8 more
wiley   +1 more source

Automatic covariate selection in logistic models for chest pain diagnosis: A new approach [PDF]

open access: yes, 2008
A newly established method for optimizing logistic models via a minorization-majorization procedure is applied to the problem of diagnosing acute coronary syndromes (ACS).
Baxt   +39 more
core   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

Tight Glycemic control in acute coronary syndromes: Prognostic implications

open access: yesEgyptian Journal of Critical Care Medicine, 2013
Background: Elevated admission plasma glucose is associated with increased mortality in patients who are admitted with acute coronary syndromes. Aim: To validate the hypothesis that tight glycemic control could reduce major adverse cardiac events in ...
Reham El-Shenawy   +3 more
doaj   +1 more source

Access and non–access site bleeding after percutaneous coronary intervention and risk of subsequent mortality and major adverse cardiovascular events:Systematic review and meta-analysis [PDF]

open access: yes, 2015
Background: The prognostic impact of site-specific major bleeding complications after percutaneous coronary intervention (PCI) has yielded conflicting data.
Buchan, Iain   +10 more
core   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

open access: yesAdvanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour   +11 more
wiley   +1 more source

Clinical Use and Measurement of Cardiac Troponin (cTn)

open access: yesProceedings of Singapore Healthcare, 2012
Cardiac troponins are cardio-specific and are widely used for the early diagnosis and triage of patients with acute coronary syndromes in conjunction with clinical history, electrocardiographic changes and imaging.
Clementine YF Yap MSc, DLM (ASCP)   +2 more
doaj   +1 more source

A comprehensive approach to the diagnosis and treatment of chronic coronary syndrome [PDF]

open access: yesБългарска кардиология, 2020
Coronary artery disease (CAD) is a chronic progressive disease with social signifi cance, result ofobstructive or non- obstructive atherosclerotic plaque accumulation in the epicardial arteries.
Velina Stoyanova
doaj   +3 more sources

Home - About - Disclaimer - Privacy