Results 171 to 180 of about 315,936 (291)

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Development and Validation of a Commercial TaqMan-Based RT-qPCR Kit for Rotavirus and Norovirus Detection in the Brazilian Acute Diarrhea Surveillance Network. [PDF]

Viruses
Cambri G, Jacomasso T, Burlandy FM, Malta FC, Fialho AM, Cilli A, Guadagnucci S, Teixeira DM, Lobo PS, Resque HR, Berto LH, Afornali A, Marchini FK, Riediger IN, Soares LS, Carmona RCC, Fumian TM.   +16 more
europepmc   +1 more source

Generation and Characterization of Monoclonal Antibodies against Swine Acute Diarrhea Syndrome Coronavirus Spike Protein. [PDF]

Int J Mol Sci, 2023
Zhou X, Zhang M, Zhang H, Ma H, Zhou J, Cao H, Guo G, Ma N, He Q, Yang Y, Lang Y, Huang Y, Li W.   +12 more
europepmc   +1 more source

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

Advanced Science, EarlyView.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao, Zhan Shi, Peng Hu, Changping Wang, Hui Wang   +4 more
wiley   +1 more source

High Frequency of Viral Etiology and Antibiotic Utilization Patterns in Pediatric Acute Diarrhea: A Cross-Sectional Study at a Tertiary Hospital in Vietnam. [PDF]

Turk Arch Pediatr
Tran KQ, Nguyen PM, Nguyen UTP, Nguyen HHT, Bui NQ.   +4 more
europepmc   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

The Prognostic Role of Serum Procalcitonin for Adult Patients with Acute Diarrhea in the Emergency Department. [PDF]

Diagnostics (Basel)
Gallo A, Covino M, Ianua' E, Piccioni A, Della Polla D, Simeoni B, Franceschi F, Landi F, Montalto M.   +8 more
europepmc   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

Management of Acute Diarrhea

Apollo Medicine, 2005
Shinjini Bhatnagar, Sarath Gopalan, Anupam Sibal   +2 more
doaj   +1 more source

Swine Acute Diarrhea Syndrome Coronavirus: An Overview of Virus Structure and Virus-Host Interactions. [PDF]

Animals (Basel)
Baek SH, Park JE.
europepmc   +1 more source