Results 141 to 150 of about 3,932,966 (340)

Cost-effectiveness analysis of influenza vaccination among the elderly in Qingdao city

Zhongguo gonggong weisheng
ObjectiveTo evaluate the cost-effectiveness of different influenza vaccination rates among the elderly population aged 65 years and above in Qingdao city.
Jinru LI, Jing JIA, Chunhui WANG, Zhaohai MENG, Xuezhao LU, Yu GAO, Kunzheng LYU   +6 more
doaj   +1 more source

Early and late complications of bariatric operation. [PDF]

, 2018
Weight loss surgery is one of the fastest growing segments of the surgical discipline. As with all medical procedures, postoperative complications will occur. Acute care surgeons need to be familiar with the common problems and their management. Although
Beekley, Alec, Davis, Kimberly A., Johnson, Dirk C., Lim, Robert   +3 more
core   +1 more source

Remarks upon the Pathology of Acute Abdominal Disease [PDF]

, 1930
Zachary Cope
openalex   +1 more source

Acute Chest Syndrome: A Rare Complication of COVID 19 in a Patient with Sickle Cell Disease

, 2022
F. Tahiri, K. Elfakiri, N. Rada, G. Draiss, M. Bouskraoui   +4 more
openalex   +1 more source

PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization [PDF]

, 2020
Athan Kuliopulos, Paul A. Gurbel, Jeffrey J. Rade, Carey Kimmelstiel, Susan E. Turner, Kevin P. Bliden, Elizabeth K. Fletcher, Daniel H. Cox, Lidija Covic, on behalf of the TRIP-PCI Investigators   +9 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Bayesian joint spatiotemporal modelling of primary infection and reinfection of HFMD at county level in Jiangsu, China, 2009–2023

BMC Public Health
Over the past decade, multiple outbreaks of hand, foot, and mouth disease (HFMD) have occurred in East Asia, especially in China. It is crucial to understand the distribution pattern and risk factors of HFMD while also studying the corresponding ...
Weijia Wang, Hong Ji, Yifan Tang, Hongfei Zhu, Wendong Liu, Kai Wang, Liguo Zhu, Chengxiu Ling, Changjun Bao, Ying Wang   +9 more
doaj   +1 more source

P509: CLONAL HEMATOPOIESIS-ASSOCIATED MUTATIONS AS MEASURABLE RESIDUAL DISEASE MARKERS IN ACUTE MYELOID LEUKEMIA PATIENTS FOLLOWING ALLOGENEIC STEM CELL TRANSPLANTATION

, 2022
Lara Bischof, Jule Ussmann, Dominic Brauer, Donata Backhaus, Lisa Herrmann, Georg‐Nikolaus Franke, Vladan Vučinić, Klaus H. Metzeler, Uwe Platzbecker, S. Schwind, Madlen Jentzsch   +10 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source