Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Review of Chagas Disease and Treatment Obstacles to Eradication [PDF]
, 2019 The World Health Organization and the Center for Disease Control reports Chagas disease, or American trypanosomiasis, as a major neglected tropical disease prevalent in 21 endemic Latin American countries.
Sherman, Emily
core +1 more source
Adhesiveness of Blood Platelets in Arteriosclerosis Obliterans, Thromboangiitis Obliterans, Acute Thrombophlebitis, Chronic Venous Insufficiency and Arteriosclerotic Heart Disease [PDF]
, 1951 Milton E. Eisen +3 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Cost-effectiveness analysis of influenza vaccination among the elderly in Qingdao city
Zhongguo gonggong weishengObjectiveTo evaluate the cost-effectiveness of different influenza vaccination rates among the elderly population aged 65 years and above in Qingdao city.
Jinru LI +6 more
doaj +1 more source
International Journal of Infectious Diseases, 2022 Background: The aim of this study was to evaluate the long-term sequelae and cognitive profiles resulting from severe hand, foot, and mouth disease (HFMD) with central nervous system (CNS) involvement.
Hong Ji +11 more
doaj
Acute disease induced cognitive dysfunction in older patients - an unrecognized syndrome. [PDF]
BMC Geriatr, 2022 Wirth R +6 more
europepmc +1 more source
An Address ON THE ACUTE EMERGENCIES OF ABDOMINAL DISEASE: Delivered before a Conjoint Meeting of the Brighton, Eastbourne, Tunbridge Wells, and Hastings Divisions of the British Medical Association [PDF]
, 1911 B. G. A. Moynihan
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Early and late complications of bariatric operation. [PDF]
, 2018 Weight loss surgery is one of the fastest growing segments of the surgical discipline. As with all medical procedures, postoperative complications will occur. Acute care surgeons need to be familiar with the common problems and their management. Although
Beekley, Alec +3 more
core +1 more source