Results 171 to 180 of about 3,932,966 (340)

Successful Treatment of Behçet's Disease Associated with Acute Myeloid Leukemia with Myelodysplasia-related Changes Using Azacitidine and Tacrolimus before Allogeneic Hematopoietic Stem Cell Transplantation

, 2017
Yukinori Nakamura, Masafumi Matsuguma, Yoshihiro Tokunaga, Kaoru Yamamoto, Mayumi Tanaka, Yoshinori Tanaka, Toshiaki Yujiri, Yukio Tanizawa   +7 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Nowcasting epidemic trends using hospital- and community-based virologic test data

Nature Communications
Population viral loads measured by reverse transcription quantitative polymerase chain reaction (RT-qPCR) cycle threshold (Ct) values are an alternative to case counts and hospitalizations for tracking epidemic trends, but their strengths, limitations ...
Tse Yang Lim, Sanjat Kanjilal, Shira Doron, Jessica A. Penney, Meredith Haddix, Tae Hee Koo, Phoebe Danza, Rebecca Fisher, Yonatan H. Grad, James A. Hay   +9 more
doaj   +1 more source

COVID-19 pathophysiology: looking beyond acute disease. [PDF]

Lancet Respir Med, 2021
The Lancet Respiratory Medicine.
europepmc   +1 more source

Pretreatment of donors with interleukin-18 attenuates acute graft-versus-host disease via STAT6 and preserves graft-versus-leukemia effects [PDF]

, 2003
Pavan Reddy, Takanori Teshima, Gerhard Hildebrandt, Debra L. Williams, Chen Liu, Kenneth R. Cooke, James L.M. Ferrara   +6 more
openalex   +1 more source

IF I MOVE, DOES IT EXPLODE? LUNG BULLAE IN INTERSTITIAL LUNG DISEASE ASSOCIATED WITH ACUTE VIRAL PNEUMONIA [PDF]

, 2023
STEVEN VELEZ PASTRANA, ADRIANA SUAREZ CRUZ   +1 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Detection of Intestinal Dysbiosis in Post-COVID-19 Patients One to Eight Months after Acute Disease Resolution. [PDF]

Int J Environ Res Public Health, 2022
Ferreira-Junior AS, Borgonovi TF, De Salis LVV, Leite AZ, Dantas AS, De Salis GVV, Cruz GNF, De Oliveira LFV, Gomes E, Penna ALB, De Oliveira GLV.   +10 more
europepmc   +1 more source

Comparison of Inflammatory and Acute-Phase Responses in the Brain and Peripheral Organs of the ME7 Model of Prion Disease [PDF]

, 2005
Colm Cunningham, David Wilcockson, Delphine Boche, V. Hugh Perry   +3 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source